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United States National Library of Medicine National Institutes of Health

Depth of Indexing and the Rule of Three

  • For most research articles, every concept substantively discussed should be covered by at least one MeSH heading
  • Even negative findings are indexed if discussed
  • For articles discussing many subjects, general headings (but as specific as possible) may be used to group related concepts rather than indexing them individually
  • Some items, such as review articles, letters, and editorials, are indexed “non-depth,” meaning:
    • All major topics are indexed
    • All minor concepts required for complete coordination of the major topics are indexed.

Rule of Three

  • More than 3 major concepts:   If more than 3 related topics are each presented as a major topic of the article, the more general MeSH heading under which they are all treed is usually designated as the major topic. The specific headings are usually indexed, but not as major topics.
  • More than 3 non-major concepts:   If more than 3 related concepts are discussed in an article but are not a major topic, the more general MeSH heading under which they are all treed is usually indexed.   The specific headings usually are not indexed.

Note: MeSH Vocabulary present on MEDLINE citations reflect the rules in place at the time of indexing.   These rules change over time.   This may explain unexpected retrieval in PubMed.

Last updated: 21 December 2007
First published: 07 March 2006
Metadata| Permanence level: Permanence Not Guaranteed