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Protein Tyrosine Phosphatases
MeSH HeadingProtein Tyrosine Phosphatases
Tree NumberD08.811.277.352.650.775
Annotationgeneral; prefer specifics
Scope NoteAn enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.
Entry TermPhosphotyrosine Phosphatase
Entry TermPhosphotyrosyl Protein Phosphatase
Entry TermProtein-Tyrosine Phosphatase
Entry TermProtein-Tyrosine-Phosphatase
Entry TermPTPase
Entry TermTyrosyl Phosphoprotein Phosphatase
Allowable QualifiersAD AE AI AN BI BL CF CH CL CS CT DE DF DU EC GE HI IM IP ME PD PH PK PO RE SD SE ST TO TU UL UR
CAS Type 1 NameProtein-tyrosine-phosphate phosphohydrolase
Registry NumberEC 3.1.3.48
Related Number79747-53-8 (CAS RN)
Previous Indexing Phosphoprotein Phosphatases (1985-1991)
History Note2008(1985)
Date of Entry19910530
Unique IDD017027


MeSH Tree Structures

 
Enzymes and Coenzymes [D08]
   Enzymes [D08.811]
      Hydrolases [D08.811.277]
         Esterases [D08.811.277.352]
            Phosphoric Monoester Hydrolases [D08.811.277.352.650]
Acid Phosphatase [D08.811.277.352.650.025]
Alkaline Phosphatase [D08.811.277.352.650.035]
Fructose-Bisphosphatase [D08.811.277.352.650.200]
Glucose-6-Phosphatase [D08.811.277.352.650.225]
Histidinol-Phosphatase [D08.811.277.352.650.300]
4-Nitrophenylphosphatase [D08.811.277.352.650.575]
Mitogen-Activated Protein Kinase Phosphatases [D08.811.277.352.650.587]  +
Nucleotidases [D08.811.277.352.650.600]  +
Phosphatidate Phosphatase [D08.811.277.352.650.620]
Phosphofructokinase-2 [D08.811.277.352.650.622]
Phosphoprotein Phosphatases [D08.811.277.352.650.625]  +
6-Phytase [D08.811.277.352.650.700]
Protein Tyrosine Phosphatases [D08.811.277.352.650.775]
Dual-Specificity Phosphatases [D08.811.277.352.650.775.250]  +
Protein Tyrosine Phosphatases, Non-Receptor [D08.811.277.352.650.775.300]  +
Receptor-Like Protein Tyrosine Phosphatases [D08.811.277.352.650.775.400]  +
SH2 Domain-Containing Protein Tyrosine Phosphatases [D08.811.277.352.650.775.700]  +
PTEN Phosphohydrolase [D08.811.277.352.650.850]

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