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Adenomatous Polyposis Coli
MeSH HeadingAdenomatous Polyposis Coli
Tree NumberC04.557.470.035.215.100
Tree NumberC04.588.274.476.411.307.089
Tree NumberC04.588.274.476.411.307.180.089
Tree NumberC04.700.100
Tree NumberC06.301.371.411.307.180.089
Tree NumberC06.405.249.411.307.180.089
Tree NumberC06.405.469.158.356.180.089
Tree NumberC06.405.469.491.307.180.089
Tree NumberC06.405.469.578.249
Tree NumberC16.320.700.100
Scope NoteA polyposis syndrome due to an autosomal dominant mutation of the APC genes ( GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood. The lifetime risk of colorectal cancer in these patients reaches 100 percent by age 60.
Entry TermAdenomatous Polyposis Coli, Familial
Entry TermAdenomatous Polyposis of the Colon
Entry TermFamilial Adenomatous Polyposis
Entry TermFamilial Adenomatous Polyposis Coli
Entry TermFamilial Adenomatous Polyposis of the Colon
Entry TermFamilial Intestinal Polyposis
Entry TermFamilial Multiple Polyposi
Entry TermFamilial Multiple Polyposis
Entry TermFamilial Multiple Polyposis Syndrome
Entry TermFamilial Polyposis Coli
Entry TermFamilial Polyposis of the Colon
Entry TermFamilial Polyposis Syndrome
Entry TermHereditary Polyposis Coli
Entry TermMyh-Associated Polyposis
Entry TermPolyposis Coli
Entry TermPolyposis Coli, Familial
Entry TermPolyposis Syndrome, Familial
Entry TermPolyposis, Adenomatous Intestinal
See AlsoAdenomatous Polyposis Coli Protein
See AlsoGardner Syndrome
See AlsoGenes, APC
Allowable QualifiersBL BS CF CH CI CL CN CO DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RA RH RI RT SC SE SU TH UL UR US VE VI
History Note1994; use POLYPOSIS SYNDROME, FAMILIAL 1987-1993; for ADENOMATOUS POLYPOSIS COLI, FAMILIAL use POLYPOSIS SYNDROME, FAMILIAL 1993
Date of Entry19860623
Unique IDD011125


MeSH Tree Structures

 
Neoplasms [C04]
   Neoplasms by Histologic Type [C04.557]
      Neoplasms, Glandular and Epithelial [C04.557.470]
         Adenoma [C04.557.470.035]
            Adenomatous Polyps [C04.557.470.035.215]
Arrow pointing to current tree nodeAdenomatous Polyposis Coli [C04.557.470.035.215.100]
Gardner Syndrome [C04.557.470.035.215.100.500]

 
Neoplasms [C04]
   Neoplasms by Site [C04.588]
      Digestive System Neoplasms [C04.588.274]
         Gastrointestinal Neoplasms [C04.588.274.476]
            Intestinal Neoplasms [C04.588.274.476.411]
               Colorectal Neoplasms [C04.588.274.476.411.307]
Arrow pointing to current tree nodeAdenomatous Polyposis Coli [C04.588.274.476.411.307.089]
Gardner Syndrome [C04.588.274.476.411.307.089.393]
Colonic Neoplasms [C04.588.274.476.411.307.180]  +
Colorectal Neoplasms, Hereditary Nonpolyposis [C04.588.274.476.411.307.190]
Rectal Neoplasms [C04.588.274.476.411.307.790]  +

 
Neoplasms [C04]
   Neoplasms by Site [C04.588]
      Digestive System Neoplasms [C04.588.274]
         Gastrointestinal Neoplasms [C04.588.274.476]
            Intestinal Neoplasms [C04.588.274.476.411]
               Colorectal Neoplasms [C04.588.274.476.411.307]
                  Colonic Neoplasms [C04.588.274.476.411.307.180]
Arrow pointing to current tree nodeAdenomatous Polyposis Coli [C04.588.274.476.411.307.180.089]
Gardner Syndrome [C04.588.274.476.411.307.180.089.500]
Sigmoid Neoplasms [C04.588.274.476.411.307.180.800]

 
Neoplasms [C04]
   Neoplastic Syndromes, Hereditary [C04.700]
Arrow pointing to current tree nodeAdenomatous Polyposis Coli [C04.700.100]
Gardner Syndrome [C04.700.100.392]
Basal Cell Nevus Syndrome [C04.700.175]
Birt-Hogg-Dube Syndrome [C04.700.212]
Colorectal Neoplasms, Hereditary Nonpolyposis [C04.700.250]  +
Dysplastic Nevus Syndrome [C04.700.305]
Exostoses, Multiple Hereditary [C04.700.330]
Hamartoma Syndrome, Multiple [C04.700.435]
Hereditary Breast and Ovarian Cancer Syndrome [C04.700.517]
Li-Fraumeni Syndrome [C04.700.600]
Multiple Endocrine Neoplasia [C04.700.630]  +
Tuberous Sclerosis [C04.700.632]
Wilms Tumor [C04.700.635]  +
Neurofibromatoses [C04.700.645]  +
Peutz-Jeghers Syndrome [C04.700.705]

 
Digestive System Diseases [C06]
   Digestive System Neoplasms [C06.301]
      Gastrointestinal Neoplasms [C06.301.371]
         Intestinal Neoplasms [C06.301.371.411]
            Colorectal Neoplasms [C06.301.371.411.307]
               Colonic Neoplasms [C06.301.371.411.307.180]
Arrow pointing to current tree nodeAdenomatous Polyposis Coli [C06.301.371.411.307.180.089]
Gardner Syndrome [C06.301.371.411.307.180.089.500]
Sigmoid Neoplasms [C06.301.371.411.307.180.800]

 
Digestive System Diseases [C06]
   Gastrointestinal Diseases [C06.405]
      Gastrointestinal Neoplasms [C06.405.249]
         Intestinal Neoplasms [C06.405.249.411]
            Colorectal Neoplasms [C06.405.249.411.307]
               Colonic Neoplasms [C06.405.249.411.307.180]
Arrow pointing to current tree nodeAdenomatous Polyposis Coli [C06.405.249.411.307.180.089]
Gardner Syndrome [C06.405.249.411.307.180.089.500]
Sigmoid Neoplasms [C06.405.249.411.307.180.800]

 
Digestive System Diseases [C06]
   Gastrointestinal Diseases [C06.405]
      Intestinal Diseases [C06.405.469]
         Colonic Diseases [C06.405.469.158]
            Colorectal Neoplasms [C06.405.469.158.356]
               Colonic Neoplasms [C06.405.469.158.356.180]
Arrow pointing to current tree nodeAdenomatous Polyposis Coli [C06.405.469.158.356.180.089]
Gardner Syndrome [C06.405.469.158.356.180.089.500]
Sigmoid Neoplasms [C06.405.469.158.356.180.800]

 
Digestive System Diseases [C06]
   Gastrointestinal Diseases [C06.405]
      Intestinal Diseases [C06.405.469]
         Intestinal Neoplasms [C06.405.469.491]
            Colorectal Neoplasms [C06.405.469.491.307]
               Colonic Neoplasms [C06.405.469.491.307.180]
Arrow pointing to current tree nodeAdenomatous Polyposis Coli [C06.405.469.491.307.180.089]
Gardner Syndrome [C06.405.469.491.307.180.089.500]
Sigmoid Neoplasms [C06.405.469.491.307.180.800]

 
Digestive System Diseases [C06]
   Gastrointestinal Diseases [C06.405]
      Intestinal Diseases [C06.405.469]
         Intestinal Polyposis [C06.405.469.578]
Arrow pointing to current tree nodeAdenomatous Polyposis Coli [C06.405.469.578.249]
Gardner Syndrome [C06.405.469.578.249.393]
Peutz-Jeghers Syndrome [C06.405.469.578.750]

 
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
   Genetic Diseases, Inborn [C16.320]
      Neoplastic Syndromes, Hereditary [C16.320.700]
Arrow pointing to current tree nodeAdenomatous Polyposis Coli [C16.320.700.100]
Gardner Syndrome [C16.320.700.100.393]
Basal Cell Nevus Syndrome [C16.320.700.175]
Birt-Hogg-Dube Syndrome [C16.320.700.212]
Colorectal Neoplasms, Hereditary Nonpolyposis [C16.320.700.250]  +
Dysplastic Nevus Syndrome [C16.320.700.305]
Exostoses, Multiple Hereditary [C16.320.700.330]
Hamartoma Syndrome, Multiple [C16.320.700.435]
Hereditary Breast and Ovarian Cancer Syndrome [C16.320.700.517]
Li-Fraumeni Syndrome [C16.320.700.600]
Multiple Endocrine Neoplasia [C16.320.700.630]  +
Tuberous Sclerosis [C16.320.700.636]
Wilms Tumor [C16.320.700.642]  +
Neurofibromatoses [C16.320.700.645]  +
Peutz-Jeghers Syndrome [C16.320.700.705]

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