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2014 MeSH

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7-Alkoxycoumarin O-Dealkylase
MeSH Heading7-Alkoxycoumarin O-Dealkylase
Tree NumberD08.811.682.690.708.170.040.024
Scope NoteA drug-metabolizing enzyme found in the hepatic, placental and intestinal microsomes that metabolizes 7-alkoxycoumarin to 7-hydroxycoumarin. The enzyme is cytochrome P-450- dependent.
Entry Term7-Ethoxycoumarin Dealkylase
Entry Term7-Ethoxycoumarin Hydroxylase
Entry Term7-Ethoxycoumarin Monooxygenase
Entry Term7-Ethoxycoumarin O-De-Ethylase
Entry Term7-Ethoxycoumarin O-Dealkylase
Entry Term7-Ethoxycoumarin O-Deethylase
Entry Term7-Propoxycoumarin O-Depropylase
Entry TermCytochrome P-450-Dependent O-Dealkylase
Entry TermEthoxycoumarin Deethylase
Entry TermEthoxycoumarin O-Deethylase
Allowable QualifiersAD AE AI AN BI BL CF CH CL CS CT DE DF DU EC GE HI IM IP ME PD PH PK PO RE SD SE ST TO TU UL UR
Registry NumberEC 1.14.13.-
Previous Indexing Oxygenases (1966-1989)
History Note90
Date of Entry19890525
Unique IDD015660


MeSH Tree Structures

 
Enzymes and Coenzymes [D08]
   Enzymes [D08.811]
      Oxidoreductases [D08.811.682]
         Oxygenases [D08.811.682.690]
            Mixed Function Oxygenases [D08.811.682.690.708]
               Cytochrome P-450 Enzyme System [D08.811.682.690.708.170]
                  Aryl Hydrocarbon Hydroxylases [D08.811.682.690.708.170.040]
Arrow pointing to current tree node7-Alkoxycoumarin O-Dealkylase [D08.811.682.690.708.170.040.024]
Aniline Hydroxylase [D08.811.682.690.708.170.040.050]
Benzopyrene Hydroxylase [D08.811.682.690.708.170.040.110]
Cytochrome P-450 CYP1A1 [D08.811.682.690.708.170.040.332]
Cytochrome P-450 CYP1A2 [D08.811.682.690.708.170.040.443]
Cytochrome P-450 CYP2B1 [D08.811.682.690.708.170.040.499]
Cytochrome P-450 CYP2D6 [D08.811.682.690.708.170.040.555]
Cytochrome P-450 CYP2E1 [D08.811.682.690.708.170.040.777]
Cytochrome P-450 CYP3A [D08.811.682.690.708.170.040.888]

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