National Library of Medicine - Medical Subject Headings

2014 MeSH

MeSH Descriptor Data

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Clomipramine
MeSH HeadingClomipramine
Tree NumberD03.494.240.194
Scope NoteA tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
Entry TermAnafranil
Entry TermChlomipramine
Entry TermChlorimipramine
Entry TermClomipramine Hydrochloride
Entry TermClomipramine Maleate (1:1)
Entry TermClomipramine Monohydrochloride
Entry TermHydiphen
Allowable QualifiersAA AD AE AG AI AN BL CF CH CL CS CT DU EC HI IM IP ME PD PK PO RE SD ST TO TU UR
Pharm. ActionAntidepressive Agents, Tricyclic
Pharm. ActionSerotonin Uptake Inhibitors
CAS Type 1 Name5H-Dibenz(b,f)azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-
Registry NumberNUV44L116D
Related Number126863-76-1 (maleate (1:1) salt)
Related Number14051-55-9 (HCl)
Related Number17321-77-6 (mono-HCl)
Related Number2LXW0L6GWJ
Related Number303-49-1 (Clomipramine)
Previous Indexing Dibenzazepines (1968-1974)
Online Noteuse CLOMIPRAMINE to search CHLORIMIPRAMINE 1975-79; use DIBENZAZEPINES 1968-74
History Note80(75); was CHLORIMIPRAMINE see under DIBENZAZEPINES 1968-79
Date of Entry19990101
Unique IDD002997


MeSH Tree Structures

 
Heterocyclic Compounds [D03]
   Heterocyclic Compounds, 3-Ring [D03.494]
      Dibenzazepines [D03.494.240]
Carbamazepine [D03.494.240.127]
Arrow pointing to current tree nodeClomipramine [D03.494.240.194]
Clozapine [D03.494.240.220]
Desipramine [D03.494.240.281]
Imipramine [D03.494.240.485]
Lofepramine [D03.494.240.520]
Mianserin [D03.494.240.550]
Opipramol [D03.494.240.625]
Trimipramine [D03.494.240.918]

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