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2014 MeSH

MeSH Descriptor Data

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Leukotrienes
MeSH HeadingLeukotrienes
Tree NumberD10.251.355.255.100.450
Tree NumberD23.469.050.175.450
Annotationeicosanoids; GEN or unspecified; prefer specifics; / biosyn / physiol permitted
Scope NoteA family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.
See AlsoReceptors, Leukotriene
Allowable QualifiersAD AE AG AN BI BL CF CH CL CS CT DF DU EC GE HI IM IP ME PD PH PK PO RE SD SE ST TO TU UR
Registry Number0
Previous Indexing Arachidonic Acids (1979-1988)
Previous Indexing Leukotrienes B (1983-1988)
Previous Indexing SRS-A (1979-1988)
History Note89
Entry Combinationantagonists & inhibitors:Leukotriene Antagonists
Date of Entry19880524
Unique IDD015289


MeSH Tree Structures

 
Lipids [D10]
   Fatty Acids [D10.251]
      Fatty Acids, Unsaturated [D10.251.355]
         Eicosanoids [D10.251.355.255]
            Arachidonic Acids [D10.251.355.255.100]
Arachidonic Acid [D10.251.355.255.100.100]
Hydroxyeicosatetraenoic Acids [D10.251.355.255.100.300]  +
Isoprostanes [D10.251.355.255.100.375]  +
Arrow pointing to current tree nodeLeukotrienes [D10.251.355.255.100.450]
Leukotriene A4 [D10.251.355.255.100.450.405]
Leukotriene B4 [D10.251.355.255.100.450.411]
SRS-A [D10.251.355.255.100.450.855]  +
Prostaglandins [D10.251.355.255.100.637]  +
Thromboxanes [D10.251.355.255.100.825]  +

 
Biological Factors [D23]
   Inflammation Mediators [D23.469]
      Autacoids [D23.469.050]
         Eicosanoids [D23.469.050.175]
Arrow pointing to current tree nodeLeukotrienes [D23.469.050.175.450]
Leukotriene A4 [D23.469.050.175.450.400]
Leukotriene B4 [D23.469.050.175.450.415]
SRS-A [D23.469.050.175.450.725]  +
Prostaglandins [D23.469.050.175.725]  +
Thromboxanes [D23.469.050.175.800]  +

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