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2014 MeSH

MeSH Descriptor Data

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Polyadenylation
MeSH HeadingPolyadenylation
Tree NumberG02.111.087.750.225.710
Tree NumberG02.149.115.750.225.710
Tree NumberG03.495.839.225.710
Tree NumberG05.355.315.700.225.710
Scope NoteThe addition of a tail of polyadenylic acid ( POLY A) to the 3' end of mRNA ( RNA, MESSENGER). Polyadenylation involves recognizing the processing site signal, (AAUAAA), and cleaving of the mRNA to create a 3' OH terminal end to which poly A polymerase ( POLYNUCLEOTIDE ADENYLYLTRANSFERASE) adds 60-200 adenylate residues. The 3' end processing of some messenger RNAs, such as histone mRNA, is carried out by a different process that does not include the addition of poly A as described here.
Allowable QualifiersDE ES GE IM PH RE
Previous Indexing Poly A/metabolism (1975-2001)
Previous Indexing RNA, Messenger/metabolism (1974-2001)
History Note2002
Date of Entry20010725
Unique IDD026723


MeSH Tree Structures

 
Chemical Phenomena [G02]
   Biochemical Phenomena [G02.111]
      Biochemical Processes [G02.111.087]
         RNA Processing, Post-Transcriptional [G02.111.087.750]
            RNA 3' End Processing [G02.111.087.750.225]
Arrow pointing to current tree nodePolyadenylation [G02.111.087.750.225.710]

 
Chemical Phenomena [G02]
   Chemical Processes [G02.149]
      Biochemical Processes [G02.149.115]
         RNA Processing, Post-Transcriptional [G02.149.115.750]
            RNA 3' End Processing [G02.149.115.750.225]
Arrow pointing to current tree nodePolyadenylation [G02.149.115.750.225.710]

 
Metabolic Phenomena [G03]
   Metabolism [G03.495]
      RNA Processing, Post-Transcriptional [G03.495.839]
         RNA 3' End Processing [G03.495.839.225]
Arrow pointing to current tree nodePolyadenylation [G03.495.839.225.710]

 
Genetic Phenomena [G05]
   Genetic Processes [G05.355]
      Gene Expression Regulation [G05.355.315]
         RNA Processing, Post-Transcriptional [G05.355.315.700]
            RNA 3' End Processing [G05.355.315.700.225]
Arrow pointing to current tree nodePolyadenylation [G05.355.315.700.225.710]

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