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Leasing Toxicological, Chemical and Directory Data

Content and Specifications
CCRIS, ChemIDplus Subset, GENE-TOX, HSDB® Subset, and TOXLINE® Subset
Click on each database name above for a description of that database. All are available for distribution in XML format via ftp.

Special note for ChemIDplus Subset: ChemIDplus structure and toxicity data available online at NLM are not available for distribution to licensees, nor does it include data with the source tag of USPDDN available in the web versions of ChemIDplus. Contact Terri Markward ( of the U.S. Pharmacopeial Convention, Inc., the provider of USPDDN data for ChemIDplus, for information about leasing USPDDN data directly from USP.

Special note for HSDB® Subset: Emergency Medical Treatment information which contains portions of the POISINDEX┬« and MEDITEXT databases is not available for distribution to licensees. To obtain this information, contact Truven Health Analytics at

Sample NLM Data
Sample data is available for prospective NLM data licensees. A license agreement is not needed for sample data.

How to Lease
NLM leases CCRIS, ChemIDplus Subset, GENE-TOX, HSDB® Subset and TOXLINE® Subset to U.S. and non-US individuals or organizations.

To request a license, complete and submit the License Request Form after reading and accepting the electronic License Agreement for NLM Data.

Alternative to Leasing
CCRIS, GENE-TOX, HSDB Subset, ChemIDplus Subset, and TOXLINE Subset records may be downloaded from the Toxicology Data Network (TOXNET).