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The research unit at the Lexington Hospital, later named the Addiction Research Center, studied the nature of the addictive process and searched for a nonaddicting painkiller as an alternative to morphine. From this research emerged methods for determining the abuse potential of new psychoactive drugs that are proposed for therapeutic use. Tracking how and where drugs exert their actions in the central nervous system, especially the brain, in order to understand how psychoactive drugs produce their rewarding effects was another aspect of their work.
c. 1965
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