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Smallpox has been one of the most devastating diseases in American history especially among Native Americans. Sporadic cases of smallpox were still being reported in the United States during the 1930s and early 1940s. The Public Health Service primarily through the work of the Hygienic Laboratory, played an important role in controlling and finally eradicating this disease. Important contributions included the inspection of vaccine being produced to ensure purity. especially from contamination with tetanus; recommending the abandonment of dressings at the vaccination site to avoid post vaccination tetanus; and the development of the multiple pressure method of vaccination.
c. 1920
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