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Biomedical Research

Controlling the spread of bubonic plague became a very important task for the Public Health Service at the turn of the twentieth century. Under the leadership of Dr. Rupert Blue (1867-1948) a major outbreak of urban bubonic plague in San Francisco, which started in 1900, was brought under control. But the infection, transmitted by flea-infected rats, had spread from rats to ground squirrels. A campaign of killing ground squirrels to obtain information on the presence of plague infection, which is pictured here, was started by Dr. Blue in rural areas around San Francisco in 1909 and then was extended to other areas of California and to other states.

c. 1910

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