TABLE OF CONTENTS
Descriptive Summary
Biographical Note
Collection Summary
Index Terms
Administrative Information
Restrictions
Series Descriptions
Personal and Biographical
Correspondence and Subject Files
Research Studies and Reprints
Diaries, 1958-1970
|
Archives and Modern Manuscripts Program, History of Medicine Division
Processed by HMD Staff
Machine-readable finding aid encoded by Dan Jenkins
| | |
|
|
| Collection Number: | MS C 191 |
| Creator: | Horsfall, Frank Lappin, 1906-1971 |
| Title: | Frank Lappin Horsfall Papers
|
| Dates: | 1940-1971 |
| Quantity: | 21 MS Boxes |
| Abstract: | Dr. Frank Horsfall was a microbiologist with the Rockefeller Hospital from 1934 to 1960, after which he became Director of the Sloan-Kettering Institute for Cancer Research until his death in 1971. Collection contains correspondence, diaries, memoranda, drafts of articles, laboratory studies and notes, reprints, printed matter, and photos. |
Dr. Frank Lappin Horsfall (1906-1971) was born in Seattle, WA. He received his B.A. from the University of Washington in 1927 and attended medical school at McGill University, graduating in 1932. Trained as a surgeon, he spent his first year after medical school at the Peter Bent Brigham Hospital in Boston as a pathologist. He developed a severe hypersensitivity to formaldehyde, forcing him to leave his pathology studies, and ultimately, surgery. He spent another resident year at Montreal's Royal Victoria Hospital and Montreal General Hospital, but realized he could not work in any environment where formaldehyde was present. Thus, in the fall of 1934, he joined the pneumonia service of the Rockefeller Institute for Medical Research, embarking on a career in microbiology and infectious diseases.
Between 1934-1937, Horsfall's work at the Rockefeller Hospital centered on immunological reactions between pneumococcal capsular polysaccharides and the antibodies to them produced by immunization of various animals. His studies resulted in the use of rabbit antisera over that of horse serum as standard pneumonia treatment. However, this advance was soon displaced by the discovery of sulfonamide drugs. In 1937, Horsfall began a four-year term with the International Health Division of the Rockefeller Foundation and marks the beginning of his devotion to the study of viruses and the diseases they cause. Here he began his work on the human influenza virus and the pneumonia virus of mice (PVM), the two most significant highlights of his laboratory research career. Horsfall returned to the Rockefeller Hospital in 1941, becoming Vice President for Clinical Studies and Physician in Chief until he left in 1960. During World War II, he served in the Naval reserves as part of the Naval Medical Research Unit at the Rockefeller Hospital, concentrating on respiratory tract diseases, specifically primary atypical pneumonia.
Horsfall's second career as Director of the Sloan-Kettering Cancer Research Center was an important one, that of a scientific statesman guiding the research of the largest private cancer research institution. His work centered around his synthesis of ideas about carcinogens, especially as they related to the role of viruses as oncogenic agents, the interaction of viruses and chemical agents, immune processes that possible modified malignant change, and the role of chemotherapy. His leadership at Sloan-Kettering came at a time of change for cancer research. The role of chemical carcinogens became the central area of study in the 1960s. Horsfall forcefully argued in a number of important publications that viral and chemical carcinogens may be interrelated, and perhaps were even interdependent. This concept of interdependency between viruses and chemicals marked an important shift in cancer etiology and resulted in rapid advances in cancer research.
Horsfall was elected to the National Academy of Sciences in 1958, and was a member of the American Philosophical Society (1956) and the American Academy of Arts and Sciences (1967). He authored over 200 publications and received several honorary degrees. His professional awards include the Eli Lily Award in Bacteriology and Immunology (1937), and the Fiftieth Anniversary Gold Medal Award of the Peter Bent Brigham Hospital (1959).
Return to the Table of Contents
Includes material relating to various science conferences, meetings, and lectures. Correspondents include Morris Fishbein, Peyton Rous, Thomas M. Rivers, Albert B. Sabin, Basil O'Conner, Jonas Salk, Stanhope Bayne-Jones, Detlev Bronk, George Corner, Rufus Cole, Abraham Flexner, P. B. Medawar, Irving H. Page, Luther Terry, David Rockefeller, Winthrop Rockefeller, Selman A. Waksman, Paul Weiss, and George H. Whipple.
Return to the Table of Contents
Restrictions
Restrictions
Collection is not restricted. Contact the Reference Staff for information regarding access. For online customer service, please visit custserv@nlm.nih.gov.
Copyright
Copyright to the collection was transferred to the public domain. See the Reference Staff for details regarding rights. For online customer service, please visit custserv@nlm.nih.gov.
Return to the Table of Contents
| | |
|
|
| These terms are indexed in the National Library of Medicine's on-line catalog LocatorPlus. Researchers wishing to find related materials should search the catalog using these terms. |
| MeSH Subjects |
| | Carcinogens |
| | Microbiology |
| | Neoplasms |
| | Oncogenic Viruses |
| | Pathology |
| | Pneumococcal Infections |
| | Pneumococcal Vaccines |
| | Pneumonia, Pneumococcal |
| | Polysaccharides, Bacterial |
| | Virology |
| Corporate Names |
| | Rockefeller Institute for Medical Research |
| | Sloan-Kettering Institute for Cancer Research |
Return to the Table of Contents
Horsfall, Frank Lappin. Frank Lappin Horsfall Papers. 1940-1971. Located in: Modern Manuscripts Collection, History of Medicine Division, National Library of Medicine, Bethesda, MD.; MS C 191.
Gift, 1975.
Return to the Table of Contents
| | | | | | | | | | | | | |
| |
Personal and Biographical
|
| Box |
| 1 | | Biographical Data |
| 1 | | Photographs |
Return to the Table of Contents
| | | | | | | | | | | | | |
| |
Correspondence and Subject Files
|
| Box |
| 1 | | Albert Lasker Awards, 1958-1960 |
| 1 | | Alumnus Summa Laude Dignatus Award (Univ. of Washington), 1962 |
| 1 | | American Academy of Art and Sciences, 1967-1971 |
| 1 | | American Association for Cancer Research, 1961-1971 |
| 1 | | American Association for the Advancement of Science, 1971 |
| 1 | | American Association of Immunologists, 1946-1971 |
| 1 | | American College of Physicians, 1968 |
| 1 | | American Medical Association, 1947-1971 |
| 1 | | American Philosophical Society, 1965-1971 |
| 2 | | American Public Health Association, 1942-1971 |
| 2 | | American Society for Clinical Investigation, 1948-1971 |
| 2 | | American Society for Microbiology, 1960-1971 |
| 2 | | Anderson Memorial Lecture (Univ. of Virginia), 1961 |
| 2 | | Association of American Medical Colleges, 1960 |
| 2 | | Association of American Physicians, 1944-1971 |
| 2 | | Babies Hospital Lecture, 1951 |
| 2 | | British Empire Cancer Campaign for Research (London), 1969 |
| 2 | | Bronk, Detlev W., 1956-1966 |
| 2 | | Cancer Section, Oklahoma Medical Research Foundation, 1966 |
| 2 | | Century Association, 1963-1971 |
| 2 | | Cole, Rufus, 1957-1967 |
| 2 | | Columbia University Graduate School of Journalism Conference, 1962 |
| 2 | | Committee on Health for Peace, 1958 |
| 2 | | Conference on Congenital Malformation, 1963 |
| 3 | | Dag Hammerskjold Fellowship Committee, 1962 |
| 3 | | Duke University Seminars, 1955 |
| 3 | | Excerpta Medica Foundation, 1958-1970 |
| 3 | | Expert Advisory Panel on Virus Disease, 1962-1971 |
| 3 | | Federation of American Societies for Experimental Biology, 1965-1971 |
| 3 | | Fifth International Poliomyelitis Conference (Copenhagen), 1960 |
| 3 | | First Conference on Congenital Malformation (London), 1960 |
| 3 | | First International American Conference on Congenital Defects, 1962 |
| 3 | | Forssman, Olof, 1952-1959 |
| 3 | | Griffis Faculty Club, (FLH, Jr., membership), 1963-1971 |
| 3 | | Harvard University, 1948 |
| 3 | | Harvey Society, 1956-1971 |
| 3 | | Health Research Council, 1958-1970 |
| 3 | | Hellenic Anticancer Society, 1965 |
| 3 | | Honorary Degree (Univ. of Alberta), 1963 |
| 3 | | IBM Research and Engineering Management Conference, 1968 |
| 3 | | Institute for Cancer Research, 1960-1970 |
| 3 | | International Cancer Congress (Moscow), 1962 |
| 3 | | International Conference on Leukemia-Lymphoma (Univ. of Michigan), 1967 |
| 4 | | International Congress for Microbiology (Montreal), 1962 |
| 4 | | Institute of Microbiology Scientific Advisory Committee, 1955-1962 |
| 4 | | International Medical Congress, 1960-1971 |
| 4 | | International Polio Congress (Geneva), 1957 |
| 4 | | Interurban Clinical Club, 1956-1971 |
| 4 | | Ito, Yohei, 1961-1968 |
| 4 | | Jackson Memorial Laboratory, 1958 |
| 4 | | James Ewing Society, 1960-1971 |
| 4 | | Journal of Immunology, 1959-1963 |
| 4 | | Kober Lecture (Georgetown University), 1964 |
| 4 | | Macy Conference, 1956 |
| 4 | | Management Advisory Council, Oak Ridge National Laboratory, 1968-1972 |
| 4 | | Mayo Foundation Lecture, 1960 |
| 4 | | McGill University (Doctor of Science Degree) [talk], 1963; 1970 |
| 4 | | Medical Library Center of New York, 1958-1971 |
| 4 | | Medical World News, 1959-1961 |
| 4 | | Montreal Medico-Chirurgical Society, 1960 |
| 4 | | National Academy of Sciences, 1963 |
| 5 | | National Academy of Sciences, 1963-1971 |
| 6 | | New York Academy of Medicine, 1950-1971 |
| 6 | | National Foundation, 1950-1971 |
| 6 | | National Tuberculosis Association Meeting (Chicago), 1959 |
| 6 | | New York Academy of Sciences, 1949-1960 |
| 6 | | New York City, Commission on Health Services, 1959 |
| 6 | | New York City, Department of Health, 1956-1965 |
| 6 | | New York City, Science and Technology Advisory Council, 1965-1971 |
| 6 | | New York Hospital - Cornell Medical Center, 1967 |
| 6 | | New York Hospital lectures, 1951-1959 |
| 6 | | New York University Hospital, 1957 |
| 6 | | Niles Memorial Lecture (Cornell University), 1962 |
| 6 | | New York Clinical Society Lecture, 1952 |
| 7 | | "On the Unity of Science", 1961 |
| 7 | | Oklahoma Medical Research Foundation, 1959-1969 |
| 7 | | Osler Society Lecture, 1965 |
| 7 | | Pan American Medical Association, 1965-1971 |
| 7 | | Perspectives in Virology, 1953-1970 |
| 7 | | Peter Bent Brigham Hospital, 50th Anniversary Gold Medal Award, 1963 |
| 7 | | Public Health Research Institute (New York City), 1957-1970 |
| 7 | | Practitioners Society of New York, 1954-1971 |
| 7 | | President's Commission on Heart Disease, Cancer and Stroke, 1964 |
| 7 | | Rivers, Thomas M., 1962-1963 |
| 7 | | Rous, Peyton, 1960-1970 |
| 8 | | Royal College of Physicians and Surgeons, (Canada) Honorary Fellowship, 1966 |
| 8 | | Royal Society of Medicine, 1958-1971 |
| 8 | | Sabin, Albert B., 1959-1965 |
| 8 | | Science Advisory Council to the New York State Legislature, 1963-1965 |
| 8 | | Seattle General Hospital Lectures, 1940 |
| 8 | | Sigma XI, (Rockefellers Institute Chapter), 1958 |
| 8 | | Sloan-Kettering Institute, 1966-1970 |
| 8 | | Society of Actuaries, 1961 |
| 9 | | Sweden-Lectures, 1946 |
| 9 | | Syracuse-Lecture, 1942 |
| 9 | | Textbook of Medicine, 1967 |
| 9 | | Tiselius, Anne, 1947-1965 |
| 9 | | Trimble Lecture - Maryland Medical and Chirurgical Faculty, 1943 |
| 9 | | Trudeau Foundation, Advisory Committee, 1957 |
| 9 | | Union Club, 1965-1971 |
| 9 | | University Club, 1961-1971 |
| 9 | | University of Washington Dedication, Health Sciences Building, 1960 |
| 9 | | U.S. Department of Defense, 1957-1970 |
| 9 | | U.S. - Japan Committee on Scientific Cooperation, 1962-1966 |
| 9 | | Viral and Rickettsial Registry, 1958-1971 |
| 9 | | Volkert, Mogens, 1946-1965 |
| 9 | | Walter M. Brickner Memorial Lecture, 1960 |
| 9 | | W.B. Saunders Company, 1961-1963 |
| 9 | | Weizmann Institute of Science, 1952-1970 |
| 9 | | World's Fair Committee, New York Academy of Medicine, 1961 |
| 9 | | World Wide Abstracts, 1958-1966 |
| 9 | | Yale Medical Society, 1951 |
| 10 | | General Correspondence |
| 11 | | Miscellaneous items, A - R |
| 12 | | Miscellaneous items, R - Z |
Return to the Table of Contents
| | | | | | | | | | | | | |
| |
Research Studies and Reprints
|
| Box |
| 13 | | Research Studies |
| 14 | | Research Studies |
| 15 | | Research Studies |
| 16 | | Research Studies |
| 17 | | Research Studies, Rivers-Horsfall book |
| 18 | | Reprints |
| 19 | | Reprints |
Return to the Table of Contents
| | | | | | | | | | | | | |
| |
Diaries, 1958-1970
|
| Box |
| 20 | | Diaries, 1958-1962 |
| 21 | | Diaries, 1963-1970 |
Return to the Table of Contents
Return to List of Manuscript Collections and Finding Aids
|
Printer-friendly Version