Amyloidosis occurs when abnormal proteins called amyloids build up and form deposits. The deposits can collect in organs such as the kidney and heart. This can cause the organs to become stiff and unable to work the way they should.
There are three main types of amyloidosis:
- Primary - with no known cause
- Secondary - caused by another disease, including some types of cancer
- Familial - passed down through genes
Symptoms can vary, depending upon which organs are affected. Treatment depends on the type of amyloidosis you have. The goal is to help with symptoms and limit the production of proteins. If another disease is the cause, it needs to be treated.
- Bone Marrow Aspiration and Biopsy (American Association for Clinical Chemistry)
- Serum Free Light Chains (American Association for Clinical Chemistry)
- Urine Protein and Urine Protein to Creatinine Ratio (American Association for Clinical Chemistry)
- AL Amyloidosis and Agent Orange (Department of Veterans Affairs)
- General Information about Plasma Cell Neoplasms (Including Multiple Myeloma) (National Cancer Institute) Available in Spanish
- ClinicalTrials.gov: Amyloidosis (National Institutes of Health)
- Genetics Home Reference: Hereditary cerebral amyloid angiopathy (National Library of Medicine)
- Genetics Home Reference: Lattice corneal dystrophy type II (National Library of Medicine)
- Genetics Home Reference: Transthyretin amyloidosis (National Library of Medicine)
Journal ArticlesReferences and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Cerebral amyloid angiopathy with and without hemorrhage: evidence for different...
- Article: Early detection of nerve injury in transthyretin-related familial amyloid polyneuropathy.
- Article: A comparison of immunohistochemistry and mass spectrometry for determining the...
- Amyloidosis -- see more articles
- Medical Help (Amyloidosis Foundation)
- Amyloidosis Foundation
- National Institute of Diabetes and Digestive and Kidney Diseases
- National Kidney and Urologic Diseases Information Clearinghouse (National Institute of Diabetes and Digestive and Kidney Diseases)