MedlinePlus Drug Information: Chlordiazepoxide and Clidinium Bromide

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Other drug names:	A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9

Chlordiazepoxide and Clidinium Bromide

(klor dye az e pox' ide) (kli di' nee um)

Contents of this page:
Why is this medication prescribed? How should this medicine be used? What special precautions should I follow? What should I do if I forget a dose? What side effects can this medication cause?	What storage conditions are needed for this medicine? In case of emergency/overdose What other information should I know? Brand names

Why is this medication prescribed? Return to top

The combination of chlordiazepoxide and clidinium bromide is used to treat ulcers and irritable bowel syndrome. It helps relieve stomach spasms and abdominal cramps.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How should this medicine be used? Return to top

The combination of chlordiazepoxide and clidinium bromide comes as a capsule to be taken by mouth. It usually is taken three or four times a day, before meals and at bedtime. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take chlordiazepoxide and clidinium bromide exactly as directed.

Chlordiazepoxide can be habit-forming. Therefore, when taking chlordiazepoxide and clidinium bromide, do not take a larger dose, take it more often, or for a longer time than your doctor tells you to. Tolerance may develop with long-term or excessive use, making this medication less effective. This medication must be taken regularly to be effective. Do not skip doses even if you feel that you do not need them. Do not take chlordiazepoxide and clidinium bromide for more than 4 months or stop taking this medication without talking to your doctor. Stopping the drug suddenly can worsen your condition and cause withdrawal symptoms (anxiousness, sleeplessness, and irritability). Your doctor probably will decrease your dose gradually.

What special precautions should I follow? Return to top

Before taking chlordiazepoxide and clidinium bromide,

tell your doctor and pharmacist if you are allergic to chlordiazepoxide, clidinium , alprazolam (Xanax), clonazepam (Klonopin), clorazepate (Tranxene), diazepam (Valium), estazolam (ProSom), flurazepam (Dalmane), lorazepam (Ativan), oxazepam (Serax), prazepam (Centrax), temazepam (Restoril), triazolam (Halcion), or any other drugs.
tell your doctor and pharmacist what prescription and nonprescription drugs you are taking, especially amantadine (Symadine, Symmetrel); antihistamines; atenolol (Tenormin); cimetidine (Tagamet); digoxin (Lanoxin); disulfiram (Antabuse); fluoxetine (Prozac); isoniazid (INH, Laniazid, Nydrazid); ketoconazole (Nizoral); levodopa (Larodopa, Sinemet); medications for depression, thyroid, high blood pressure, seizures, Parkinson's disease, asthma, colds, or allergies; oral contraceptives; muscle relaxants; probenecid (Benemid, Probalan); propoxyphene (Darvon); propranolol (Inderal); rifampin (Rifadin); sedatives; theophylline (Theo-Dur); tranquilizers; sleeping pills;valproic acid (Depakene); or vitamins. These medications may add to the drowsiness caused by chlordiazepoxide and clidinium bromide.
tell your doctor if you have or have ever had glaucoma; prostate problems; high blood pressure; seizures; or lung, thyroid, kidney, heart, or liver disease.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking this medication, call your doctor immediately.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking chlordiazepoxide and clidinium bromide.
you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how it affects you.
remember that alcohol can add to the drowsiness caused by this medication.
tell your doctor if you use tobacco products. Cigarette smoking may decrease the effectiveness of this medication.

What should I do if I forget a dose? Return to top

If you take several doses per day and miss a dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause? Return to top

Side effects from chlordiazepoxide and clidinium bromide are common and include:

upset stomach
drowsiness
weakness or tiredness
excitement
sleeplessness
dry mouth
heartburn
bloated feeling
eyes more sensitive to sunlight than usual
taste changes
changes in appetite

Tell your doctor if any of these symptoms are severe or do not go away:

constipation
difficulty urinating
frequent urination
blurred vision
dilated pupils
changes in sex drive or ability

If you experience any of the following symptoms, call your doctor immediately:

jaw, neck, and back muscle spasms
slow or difficult speech
shuffling walk
persistent, fine tremor or inability to sit still
fever
difficulty breathing or swallowing
severe skin rash
yellowing of the skin or eyes
irregular heartbeat

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine? Return to top

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose Return to top

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What other information should I know? Return to top

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names Return to top

Clindex®

Librax®

Last Revised - 07/01/2007
Last Reviewed - 05/01/2008

American Society of Health-System Pharmacists, Inc. Disclaimer