The combination of methyldopa and hydrochlorothiazide is used to treat high blood pressure. Methyldopa works by relaxing the blood vessels so that blood can flow more easily through the body. Hydrochlorothiazide helps to lower blood pressure by eliminating unneeded water and salt from the body.
High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
This medication comes as a tablet to take by mouth. It usually is taken two or three times a day. To help you remember to take methyldopa and hydrochlorothiazide, take it around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take methyldopa and hydrochlorothiazide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
This medication controls high blood pressure but does not cure it. Continue to take methyldopa and hydrochlorothiazide even if you feel well. Do not stop taking methyldopa and hydrochlorothiazide without talking to your doctor.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
talk to your doctor about the risks and benefits of taking methyldopa and hydrochlorothiazide if you are 65 years of age or older. Older adults should not usually take methyldopa and hydrochlorothiazide because it is not as safe as other medications that can be used to treat the same condition.
Your doctor may prescribe a low-salt or low-sodium diet. Follow these directions carefully.
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
loss of appetite
muscle weakness or cramps
yellowing of the skin or eyes
swollen ankles or feet
This medication may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Keep all appointments with your doctor and the laboratory. Your blood pressure should be checked regularly to determine your response to methyldopa and hydrochlorothiazide.
To relieve dry mouth caused by methyldopa and hydrochlorothiazide, chew gum or suck sugarless hard candy.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Last Revised - 02/15/2015
AHFS® Consumer Medication Information. © Copyright, 2015. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.