Rectal morphine is used to relieve moderate to severe pain. Morphine is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the body senses pain.
Rectal morphine comes as a suppository to insert in the rectum. It is usually inserted every 4 hours. Use rectal morphine at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use morphine exactly as directed.
Your doctor may adjust your dose of morphine during your treatment to control your pain as well as possible. If you feel that your pain is not controlled, call your doctor. Do not change the dose of your medication without talking to your doctor.
Morphine may be habit-forming. Do not use a larger dose, use it more often, or use it for a longer period of time than prescribed by your doctor.
Do not stop using morphine without talking to your doctor. Your doctor may decrease your dose gradually. If you suddenly stop using morphine, you may experience withdrawal symptoms such as anxiety; sweating; difficulty falling asleep or staying asleep; chills; shaking of a part of your body that you cannot control; nausea; diarrhea; runny nose, sneezing or coughing; hair on your skin standing on end; or hallucinating (seeing things or hearing voices that do not exist).
Remove the wrapper.
Dip the tip of the suppository in water.
Lie down on your left side and raise your right knee to your chest (A left-handed person should lie on the right side and raise the left knee.)
Using your finger, insert the suppository about 1 inch (2.5 centimeters) into the rectum.
Hold it in place with your finger for a few moments
Stand up after about 15 minutes. Wash your hands thoroughly and resume normal activities.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Drink plenty of fluids while you are using this medication.
Insert the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not insert a double dose to make up for a missed one.
difficulty falling asleep or staying asleep
loss of appetite
decreased sexual desire or ability
slowed, shallow, or irregular breathing
blue or purple color to the skin
fast, slow, or pounding heartbeat
swelling of the arms, hands, feet, ankles, or lower legs
Morphine may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
Store rectal morphine in a safe place so that no one else can use it accidentally or on purpose. Keep track of how many suppositories are left so you will know if any are missing.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
slow, shallow, or irregular breathing
blue or purple color to the skin
loss of consciousness
cold, clammy skin
Keep all appointments with your doctor.
This prescription is not refillable. If you are taking morphine to control your pain on a long-term basis, be sure to schedule appointments with your doctor so that you do not run out of medication. If you are using morphine on a short term basis, call your doctor if you continue to experience pain after you finish the medication.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Last Reviewed - 02/01/2009
AHFS® Consumer Medication Information. © Copyright, 2015. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.