Skip navigation

Ciprofloxacin and Hydrocortisone Otic

pronounced as(sip roe flox' a sin) (hye droe kor' ti sone)

Why is this medication prescribed?

Ciprofloxacin and hydrocortisone otic is used to treat outer ear infections in adults and children. Ciprofloxacin is in a class of medications called quinolone antibiotics. Hydrocortisone is in a class of medications called corticosteroids. The combination of ciprofloxacin and hydrocortisone works by killing the bacteria that cause infection and reducing swelling in the ear.

How should this medicine be used?

Ciprofloxacin and hydrocortisone otic comes as a suspension (liquid) to place into the ear. It is usually used twice a day, in the morning and evening, for 7 days. Use ciprofloxacin and hydrocortisone otic at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use ciprofloxacin and hydrocortisone otic exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Ciprofloxacin and hydrocortisone otic is only for use in the ears. Do not use in the eyes.

You should begin to feel better during the first few days of treatment with ciprofloxacin and hydrocortisone otic. If your symptoms do not improve after one week or get worse, call your doctor.

Use ciprofloxacin and hydrocortisone otic until you finish the prescription, even if you feel better. If you stop using ciprofloxacin and hydrocortisone otic too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

To use the eardrops, follow these steps:

  1. Hold the bottle in your hand for 1 or 2 minutes to warm the solution.

  2. Shake the bottle well.

  3. Lie down with the affected ear upward.

  4. Place the prescribed number of drops into your ear.

  5. Be careful not to touch the tip to your ear, fingers, or any other surface.

  6. Remain lying down with the affected ear upward for 30-60 seconds.

  7. Repeat steps 1-6 for the opposite ear if necessary.

Other uses for this medicine

Return to top

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Return to top

Before using ciprofloxacin and hydrocortisone otic,

  • tell your doctor and pharmacist if you are allergic to ciprofloxacin (Cipro), hydrocortisone (Cortaid, Cortef, Cortizone, Hytone), cinoxacin (Cinobac) (not available in the U.S.), enoxacin (Penetrex) (not available in the U.S.), gatifloxacin (Tequin) (not available in the U.S.), gemifloxacin (Factive), levofloxacin (Levaquin), lomefloxacin (Maxaquin), moxifloxacin (Avelox), nalidixic acid (NegGram), norfloxacin (Noroxin), ofloxacin (Floxin), sparfloxacin (Zagam) (not available in the U.S.), trovafloxacin and alatrofloxacin combination (Trovan) (not available in the U.S.), or any other medications.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
  • tell your doctor if you have a hole in your ear drum(s) or ear tube(s). Your doctor will tell you not to use this medication.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using ciprofloxacin and hydrocortisone otic, call your doctor.
  • you should know that you must keep your infected ear(s) clean and dry while using ciprofloxacin and hydrocortisone otic. Avoid getting the infected ear(s) wet while bathing, and avoid swimming unless your doctor has told you otherwise.

What special dietary instructions should I follow?

Return to top

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Return to top

Apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use extra eardrops to make up for a missed dose.

What side effects can this medication cause?

Return to top

Ciprofloxacin and hydrocortisone otic may cause side effects. Tell your doctor if the following symptom is severe or does not go away:

  • headache

Some side effects can be serious. If you experience any of these symptoms, stop using ciprofloxacin and hydrocortisone otic and call your doctor immediately:

  • rash

  • hives

  • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

  • hoarseness

  • difficulty swallowing or breathing

Ciprofloxacin and hydrocortisone otic may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

What should I know about storage and disposal of this medication?

Return to top

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Avoid freezing and protect from light. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

Return to top

If someone swallows ciprofloxacin and hydrocortisone otic, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What other information should I know?

Return to top

Keep all appointments with your doctor.

Do not let anyone else use your medication. Your prescription is probably not refillable.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names of combination products

Return to top
  • Cipro® HC (containing Ciprofloxacin, Hydrocortisone)

Last Reviewed - 08/01/2010

ASHP Logo American Society of Health-System Pharmacists, Inc. Disclaimer

AHFS® Consumer Medication Information. © Copyright, 2014. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.