Pegaptanib injection is used to treat wet age-related macular degeneration (AMD; an ongoing disease of the eye that causes loss of the ability to see straight ahead and may make it more difficult to read, drive, or perform other daily activities). Pegaptanib injection is in a class of medications called vascular endothelial growth factor (VEGF) antagonists. It works by stopping abnormal blood vessel growth and leakage in the eye(s) that may cause vision loss in people with wet AMD.
Pegaptanib injection comes as a solution (liquid) to be injected into the eye by a doctor. It is usually given in a doctor's office once every 6 weeks.
Before you receive a pegaptanib injection, your doctor will clean your eye to prevent infection and numb your eye to reduce discomfort during the injection. You may feel pressure in your eye when the medication is injected. After your injection, your doctor will need to examine your eyes before you leave the office.
Pegaptanib controls wet AMD, but does not cure it. Your doctor will watch you carefully to see how well pegaptanib works for you. Talk to your doctor about how long you should continue treatment with pegaptanib.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Unless your doctor tells you otherwise, continue your normal diet.
If you miss an appointment to receive pegaptanib, call your doctor as soon as possible.
difficulty breathing or swallowing
swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
eye redness or pain
sensitivity to light
change or decrease in vision
floaters in the eye
seeing flashes of light
swelling of the eyelid
Pegaptanib injection may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Keep all appointments with your doctor. Your doctor will need to examine your eyes to see if you are developing serious side effects within 2 to 7 days after you receive each pegaptanib injection.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Last Revised - 02/15/2012
AHFS® Consumer Medication Information. © Copyright, 2013. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.