Ezogabine is used along with other medications to control partial onset seizures (seizures that involve only one part of the brain) in adults. Ezogabine is in a class of medications called anticonvulsants. It works by reducing abnormal electrical activity in the brain.
Ezogabine comes as a tablet to take by mouth. It is usually taken with or without food three times a day. Take ezogabine at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
Swallow the tablets whole; do not split, chew, dissolve, or crush them.
Your doctor will probably start you on a low dose of ezogabine and gradually increase your dose, not more than once every week.
Take ezogabine exactly as prescribed. Ezogabine may be habit forming. Do not take a larger dose, take it more often, or take it for a longer period of time than prescribed by your doctor.
Ezogabine may help control your condition but will not cure it. It may take a few weeks or longer before you feel the full benefit of ezogabine. Continue to take ezogabine even if you feel well. Do not stop taking ezogabine without talking to your doctor, even if you experience side effects such as unusual changes in behavior or mood. If you suddenly stop taking ezogabine, your seizures may happen more often. Your doctor will probably decrease your dose gradually over at least 3 weeks.
Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with ezogabine and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer's website to obtain the Medication Guide.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
tell your doctor if you are pregnant, plan to become pregnant or are breastfeeding. If you become pregnant while taking ezogabine, call your doctor.
Unless your doctor tells you otherwise, continue your normal diet.
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
problems with coordination, balance, or walking
drowsiness, confusion, or trouble concentrating
difficulty or inability to speak or understand speech or written language
feelings of numbness, tingling, pricking, burning, or creeping on the skin
uncontrollable shaking of a part of the body
abnormal color of urine
inability to begin urinating
changes in color (blue) of skin, lips, or fingernails
changes in vision
pain when urinating
weak urine stream
difficulty emptying your bladder
blood in urine
difficulty thinking clearly, understanding reality, or using good judgment
hallucinations (seeing things or hearing voices that do not exist)
Ezogabine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
Store ezogabine in a safe place so that no one else can take it accidentally or on purpose. Keep track of how many tablets are left so you will know if any are missing.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Your doctor will probably order regular eye examinations while you are taking this medication. Keep all appointments with your doctor and eye doctor.
Do not let anyone else take your medication. Ezogabine is a controlled substance. Prescriptions may be refilled only a limited number of times; ask your pharmacist if you have any questions.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Last Revised - 10/15/2013
AHFS® Consumer Medication Information. © Copyright, 2014. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.