Vincristine lipid complex should be administered only into a vein. However, it may leak into surrounding tissue causing severe irritation or damage. Your doctor or nurse will monitor your administration site for this reaction. If you experience any of the following symptoms, call your doctor immediately: pain, itching, redness, swelling, blisters, or sores in the place where the medication was injected.
Vincristine lipid complex should be given only under the supervision of a doctor with experience in the use of chemotherapy medications.
Vincristine lipid complex is used to treat a certain type of acute lymphoblastic leukemia (ALL; a type of cancer of the white blood cells) that has not improved or that has worsened after at least two different treatments with other medications. Vincristine lipid complex is in a class of medications called vinca alkaloids. It works by slowing or stopping the growth of cancer cells in your body.
Vincristine lipid complex comes as a liquid to be injected intravenously (into a vein) over 1 hour by a doctor or nurse in a medical facility. It is usually given once every 7 days. The length of treatment depends on the types of drugs you are taking, how well your body responds to them.
Your doctor may need to delay your treatment or change your dose if you experience certain side effects. It is important for you to tell your doctor how you are feeling during your treatment with vincristine lipid complex.
Your doctor may tell you to take a stool softener or laxative to help prevent constipation during your treatment with vincristine lipid complex.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
You should eat plenty of fiber, including fruits and vegetables, and drink plenty of fluids during your treatment to help prevent constipation.
loss of appetite
trouble falling asleep or staying asleep
pain, itching, redness, swelling, blisters, or sores in the place where the medication was injected
fever, sore throat, ongoing cough and congestion, or other signs of infection
unusual bleeding or bruising
bloody or black, tarry stools
unusual tiredness or weakness
pain, burning, tingling, weakness in the hands or feet
increased or decreased feeling or sensitivity to touch
decreased or absent reflexes
muscle or joint pain
sudden changes in vision
sudden decrease or loss of hearing
confusion or memory loss
sudden weakness on one side of the face
Vincristine may increase the risk that you will develop other cancers. Talk to your doctor about the risks of receiving vincristine lipid complex.
Vincristine lipid injection may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
weakness in the hands or feet
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to vincristine lipid complex.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Last Revised - 06/15/2013
AHFS® Consumer Medication Information. © Copyright, 2013. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.