Hydromorphone suppositories are used to relieve moderate to severe pain. Hydromorphone is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the brain and nervous system respond to pain.
Hydromorphone comes as a suppository to insert in the rectum. It is usually inserted once every 6 to 8 hours. Insert hydromorphone at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use hydromorphone suppositories exactly as directed.
Hydromorphone suppositories may be habit forming. Do not use a larger dose, use them more often, or use them for a longer period of time than prescribed by your doctor.
Do not stop using hydromorphone suppositories without talking to your doctor. If you suddenly stop using hydromorphone suppositories, you may experience withdrawal symptoms including restlessness, teary eyes, runny nose, yawning, sweating, chills, hair standing on end, muscle and joint pain, widening of the pupils (black circles in the middle of the eyes), irritability, anxiety, backache, weakness, stomach cramps, difficulty falling asleep or staying asleep, nausea, loss of appetite, vomiting, diarrhea, fast breathing, or fast heartbeat. Your doctor will probably decrease your dose gradually.
Remove the wrapper.
Dip the tip of the suppository in water.
Lie down on your left side and raise your right knee to your chest (a left-handed person should lie on the right side and raise the left knee).
Using your finger, insert the suppository about 1 inch (2.5 centimeters) into the rectum.
Hold it in place with your finger for a few moments.
Stand up after about 15 minutes. Wash your hands thoroughly and resume normal activities.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using hydromorphone suppositories, call your doctor.
Unless your doctor tells you otherwise, continue your normal diet.
Use the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for a missed one.
narrowing of the pupils (dark circles in the center of the eyes)
slowed or stopped breathing
breathing that is irregular or that stops and starts
Hydromorphone suppositories may cause other side effects. Call your doctor if you have any unusual problems while you are using this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it in the refrigerator. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
Store hydromorphone suppositories in a refrigerator in a safe place so that no one else can take the medication accidentally or on purpose. Keep track of how many suppositories are left so you will know if any are missing.
In case of overdose or if someone swallows hydromorphone suppositories, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
slowed or stopped breathing
coma (loss of consciousness for a period of time)
cold, clammy skin
narrowing or widening of the pupils (dark circle in the middle of the eye)
slowed or stopped heartbeat
Keep all appointments with your doctor.
This prescription is not refillable. If you continue to have pain after you finish the hydromorphone suppositories, call your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Last Revised - 08/15/2013
AHFS® Consumer Medication Information. © Copyright, 2015. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.