In clinical studies, more patients who were treated with tigecycline injection for serious infections died than patients who were treated with other medications for serious infections. These people died because their infections worsened, because they developed complications of their infections, or because of other medical conditions they had. There is not enough information to tell whether using tigecycline injection increases the risk of death during treatment. Your doctor will only treat you with tigecycline injection if other medication cannot be used to treat your infection.
Talk to your doctor about the risk of using tigecycline injection.
Tigecycline injection used to treat certain serious infections including community acquired pneumonia (a lung infection that developed in a person who was not in the hospital), skin infections, and infections of the abdomen (area between the chest and the waist). Tigecycline injection should not be used to treat pneumonia that developed in people who were in a hospital or foot infections in people who have diabetes. Tigecycline injection is in a class of antibiotics called tetracyclines. It works by killing bacteria that cause infection. Antibiotics will not work for colds, flu, or other viral infections.
Tigecycline injection comes as a powder to be mixed with fluid and injected into a vein. It is usually infused (injected slowly) intravenously (into a vein) over a period of 30 to 60 minutes, once every 12 hours. The length of your treatment depends on the type of infection you have and how your body responds to the medication.
You may receive tigecycline injection in a hospital or you may use the medication at home. Follow the directions on your prescription label carefully, and ask your doctor or other healthcare provider to explain any part you do not understand. Use tigecycline injection exactly as directed. Do not infuse it more quickly than directed. Do not use more or less of it or use it more often than prescribed by your doctor.
If you will be using tigecycline injection at home, your healthcare provider will show you how to infuse the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions. Ask your healthcare provider what to do if you have any problems infusing tigecycline injection.
You should begin to feel better during the first few days of treatment with tigecycline injection. If your symptoms do not improve or get worse, call your doctor.
Use tigecycline injection until you finish the prescription, even if you feel better. If you stop using tigecycline injection too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Unless your doctor tells you otherwise, continue your normal diet.
Infuse the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for a missed one.
loss of appetite
severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps (may occur up to 2 months or more after your treatment)
blistering or peeling skin
tingling or swelling of the face, neck, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
difficulty breathing or swallowing
yellowing of the skin or eyes
sore throat, fever, chills, and other signs of new or worsening infection
Tigecycline injection may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].
Your healthcare provider will tell you how to store your medication. Store your medication only as directed. Make sure you understand how to store your medication properly. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to tigecycline injection.
If you still have symptoms of infection after you finish tigecycline injection, call your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Last Revised - 01/15/2014
AHFS® Consumer Medication Information. © Copyright, 2014. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.