Ramucirumab injection may cause severe bleeding that can be life-threatening and even cause death. If you experience any of the following symptoms, call your doctor immediately: coughing up or vomiting blood or material that looks like coffee grounds, unusual bleeding or bruising, pink, red, or dark brown urine, red or tarry black bowel movements, lightheadedness, nosebleeds, other unusual bleeding or bruising. Your doctor may stop ramucirumab injection if you experience severe bleeding.
Ramucirumab injection is used to treat stomach cancer or cancer located in the area where the stomach meets the esophagus (the tube between the throat and stomach) when these conditions do not improve after treatment with other medications. Ramucirumab injection is in a class of medications called monoclonal antibodies. It works by stopping the growth of cancer cells.
Ramucirumab injection comes as a liquid to be injected into a vein over 60 minutes by a doctor or nurse in a hospital or medical facility. It is usually given once every 2 weeks. The length of your treatment depends on how well your body responds to the medication and the side effects that you experience.
Your doctor may need to interrupt or stop your treatment if you experience certain side effects. Your doctor will give you other medications to prevent or treat certain side effects before you receive each dose of ramucirumab injection. Tell your doctor or nurse if you experience any of the following while you receive ramucirumab: uncontrollable shaking of a part of the body; back pain or spasms; chest pain and tightness; chills; flushing; shortness of breath; wheezing; pain, burning, numbness, pricking, or tingling in the hands or feet or on the skin; breathing difficulties; fast heartbeat.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Unless your doctor tells you otherwise, continue your normal diet.
Call your doctor right away if you are unable to keep an appointment to receive a dose of ramucirumab injection.
sudden weakness of an arm or leg
drooping of one side of the face
difficulty speaking or understanding
crushing chest or shoulder pain
slow or difficult speech
shortness of breath
severe diarrhea, vomiting, or stomach pain
Ramucirumab injection may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to ramucirumab injection.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Last Revised - 06/15/2014
AHFS® Consumer Medication Information. © Copyright, 2015. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.