Stavudine, when used alone or in combination with other antiviral medications, may cause serious and possibly deadly damage to the liver and pancreas and a life-threatening condition called lactic acidosis. Tell your doctor if you have or have ever had liver or pancreas disease or gallstones, and if you have taken medication to treat HIV for a long time. Also tell your doctor if you drink or have ever drunk large quantities of alcohol and if you are taking didanosine (Videx) or hydroxyurea (Droxia, Hydrea). Tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while taking stavudine, call your doctor.
If you experience any of the following symptoms, call your doctor immediately: upset stomach, vomiting, unusual or unexpected stomach pain, sudden weight loss, extreme weakness or tiredness, shortness of breath, fast breathing, weakness in arms or legs, and any sudden change in your general health. Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to stavudine.
Stavudine is used along with other medications to treat human immunodeficiency virus (HIV) infection. Stavudine is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV in the blood. Although stavudine does not cure HIV, it may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer. Taking these medications along with practicing safer sex and making other life-style changes may decrease the risk of transmitting (spreading) the HIV virus to other people.
Stavudine comes as a capsule and a solution (liquid) to take by mouth. It is usually taken twice a day (every 12 hours), with or without food and with plenty of water. To help you remember to take stavudine, take it at around the same time each day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take stavudine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
If you are giving the oral solution to a child, shake the bottle well before each use to mix the medication evenly. Use the measuring cup provided to measure the child's dose.
Stavudine controls HIV infection but does not cure it. Continue to take stavudine even if you feel well. Do not stop taking stavudine without talking to your doctor. If you miss doses or suddenly stop taking stavudine, your condition may become more difficult to treat.
Stavudine is also sometimes used in combination with other medications to prevent HIV infection in health care workers or other people who were accidentally exposed to HIV. Talk to your doctor about the possible risks of using this medication for your condition.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Unless your doctor tells you otherwise, continue your normal diet.
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
numbness, tingling, burning or pain in the hands or feet
difficulty moving your hands and feet
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the capsules at room temperature and away from excess heat and moisture (not in the bathroom). Store the solution in the refrigerator and throw away the unused portion after 30 days. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
numbness, tingling, or pain in the hands or feet
difficulty moving hands or feet
unusual or unexpected stomach pain
weakness or tiredness
shortness of breath
weakness in arms and legs
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Last Revised - 10/15/2012
AHFS® Consumer Medication Information. © Copyright, 2014. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.