Amprenavir will no longer be available in the U.S. after March, 2008. If you are currently using amprenavir, you should call your doctor to discuss switching to another treatment.
Amprenavir liquid should not be used by infants or children younger than 4 years of age, pregnant women, patients with liver or kidney failure, or patients taking disulfiram (Antabuse) or metronidazole (Flagyl). Amprenavir liquid should only be used when you cannot take amprenavir capsules or other antiretroviral agents. If you are using the liquid, but believe you could take capsules, you should speak to your doctor.
Amprenavir is used in combination with other antiretroviral medications to treat human immunodeficiency virus (HIV). Amprenavir belongs to a class of drugs called protease inhibitors, which slow the spread of HIV infection in the body.
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Amprenavir comes as a capsule and liquid to take by mouth. It is usually taken twice a day. Amprenavir may be taken with or without food. However, avoid taking amprenavir with high-fat foods or high-fat meals. The amount of drug in amprenavir capsules is not the same as the amount in amprenavir liquid. Do not switch between amprenavir capsules and amprenavir liquid unless your doctor tells you how many amprenavir capsules or how much amprenavir liquid you should take. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take amprenavir exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Amprenavir is not a cure and may not decrease the number of HIV-related illnesses. Amprenavir does not prevent the spread of HIV to other people. Continue to take amprenavir even if you feel well. Do not stop taking amprenavir without talking to your doctor.
Do not take vitamin E supplements if you are taking amprenavir. Amprenavir capsules and solutions contain vitamin E and you do not need to take additional vitamin E to meet the daily requirement for this vitamin.
If you miss a dose by less than 4 hours, take the missed dose as soon as you remember it. If you miss a dose by more than 4 hours, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
upset stomach and vomiting
shortness of breath
breath that smells fruity
diarrhea or loose stools
change in taste
tingling sensation around your mouth
seizures (if you are taking the liquid)
confusion (if you are taking the liquid)
rapid heart rate (if you are taking the liquid)
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
It is important that you do not run out of your supply of amprenavir or other antiviral medications because the amount of HIV in your blood may increase if you stop taking them. When your supply of amprenavir is low, make sure you contact your doctor or pharmacist for a refill.
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to amprenavir.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Last Revised - 04/13/2012
AHFS® Consumer Medication Information. © Copyright, 2013. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.