What is it?
Panax ginseng is a plant. People use the root to make medicine. Do not confuse Panax ginseng with American ginseng, Siberian ginseng, or Panax pseudoginseng. See the separate listings for American ginseng and Siberian ginseng.
Panax ginseng is used for improving thinking, concentration, memory and work efficiency, physical stamina, and athletic endurance.
Some people use Panax ginseng to help them cope with stress and as a general tonic for improving well-being. They sometimes call Panax ginseng an “adaptogen” when it’s used in this way.
Panax ginseng is also used for depression, anxiety, chronic fatigue syndrome (CFS), for boosting the immune system, and for fighting particular infections in a lung disease called cystic fibrosis. These infections are caused by a bacterium named Pseudomonas.
Some people use Panax ginseng to treat breast cancer and prevent ovarian cancer, liver cancer, lung cancer, and skin cancer.
Other uses include treatment of anemia, diabetes, inflammation of the stomach lining (gastritis), fever, hangover, chronic obstructive pulmonary disease (COPD), and asthma.
Panax ginseng is also used for bleeding disorders, loss of appetite, vomiting, intestinal problems, fibromyalgia, sleeping problems (insomnia), nerve pain, joint pain, dizziness, headache, convulsions, disorders of pregnancy and childbirth, hot flashes due to menopause, and to slow the aging process.
Some men use Panax ginseng on the skin of the penis as part of a multi-ingredient product for treating early orgasm (premature ejaculation). Men also use it for erectile dysfunction (ED). There is some evidence that Panax ginseng is effective for these uses.
In manufacturing, Panax ginseng is used to make soaps, cosmetics, and as a flavoring in beverages.
Ginseng has been used as a medicine for over two thousand years. Today, approximately 6 million Americans use it regularly.
Some people consider the age of the ginseng roots important. In 1976, a 400-year-old root of Manchurian ginseng from the mountains of China reportedly sold for $10,000 per ounce.
In Western medicine, Panax ginseng is used as a stimulant to make people more active. But, in contrast, in Traditional Chinese Medicine (TCM), Panax ginseng is used to make people feel calmer. It is also widely used in China for the heart and blood vessels. Higher doses are generally used in TCM than in Western medicine.
Be aware that Panax ginseng products are not always what they claim. The contents of products labeled as containing Panax ginseng can vary greatly. Many contain little or no Panax ginseng.
Panax ginseng interacts with many prescription drugs. See the section below titled “Are there any interactions with medications?” If you take medications, talk to your healthcare provider before taking Panax ginseng.
How effective is it?
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
The effectiveness ratings for GINSENG, PANAX are as follows:
Possibly effective for...
- Alzheimer’s disease. Evidence shows that taking Panax ginseng root daily for 12 weeks can improve mental performance in people with Alzheimer’s disease.
- Lung disease called chronic obstructive pulmonary disease (COPD). Taking Panax ginseng by mouth seems to improve lung function and some symptoms of COPD.
- Mental function. Taking Panax ginseng by mouth might improve abstract thinking, mental arithmetic skills, and reaction times in healthy, middle-aged people but not in young adults. Panax ginseng alone does not seem to improve memory, but there is some evidence that a combination of Panax ginseng and ginkgo leaf extract can improve memory in otherwise healthy people between the ages of 38 and 66.
- Erectile dysfunction (ED). Taking Panax ginseng by mouth seems to improve sexual function in men with erectile dysfunction.
- High blood pressure. Early evidence shows that taking Panax ginseng might slightly decrease blood pressure in people with high blood pressure.
- Premature ejaculation. Applying a cream containing Panax ginseng, angelica root, Cistanches deserticola, Zanthoxyl species, torlidis seed, clover flower, asiasari root, cinnamon bark, and toad venom (SS Cream) to the penis one hour before intercourse and washing off immediately before intercourse seems to help prevent premature ejaculation
- Sexual arousal. Taking powdered Korean red ginseng, a specific form of Panax ginseng, seems to improve sexual arousal and satisfaction in postmenopausal women. Also, using a specific product containing Korean red ginseng and other ingredients (ArginMax) seems to improve sexual desire in women.
Possibly ineffective for...
- Athletic performance. Taking Panax ginseng by mouth for up to 8 weeks does not improve exercise performance.
Insufficient evidence to rate effectiveness for...
- Bad breath. Early evidence suggests that taking Korean red ginseng, a type of Panax ginseng, daily for 10 weeks helps reduce bad breath, particularly in people with bad breath caused by Helicobacter pylori (H. pylori) infection.
- Breast cancer. Some studies conducted in China suggest that some people with breast cancer treated with any form of ginseng (American or Panax) have a higher quality of life and lower risk of death. However, this might not be a result of taking the ginseng, because the people in the study were also more likely to be treated with the prescription cancer drug tamoxifen. It is difficult to know how much of the benefit to attribute to ginseng.
- Infection of the airways in the lung (bronchitis). Taking Panax ginseng, combined with antibiotics, might be more effective in killing bacteria than antibiotic treatment alone.
- Cancer. Research suggests that taking ginseng by mouth might decrease the occurrence of some types of cancer, including stomach cancer, lung cancer, liver cancer, ovarian cancer, and skin cancer. Also, early research suggests that taking Panax ginseng (Cultivated Wild Ginseng Pharmacopuncture) intravenously (by IV) might stop or slow the progression of lung cancer.
- Common cold. There is some evidence that taking a specific Panax ginseng extract (G115) by mouth can decrease the chance of catching a cold.
- Heart failure. Administering ginseng intravenously (by IV) seems to improve symptoms of heart failure.
- Diabetes. There is inconsistent evidence about the effects of Panax ginseng on diabetes. Some research shows that taking Panax ginseng by mouth daily can improve blood sugar levels. However, other research suggests that taking Panax ginseng (AIPOP, Gangdown-Do, Korea) or Korean red ginseng extract (Spectrum Laboratories, Gardena, CA) by mouth does not improve blood sugar levels in people with diabetes.
- Fatigue. Early evidence shows that taking a specific product containing Panax ginseng, vitamins, and minerals (Pharmaton) might reduce symptoms of fatigue.
- HIV. Early evidence shows that Korean red ginseng, a particular form of Panax ginseng, might increase immune function but does not affect how much of the HIV virus is circulating in the blood of people with HIV
- Prediabetes. Taking a combination of Korean red ginseng and cheonggukjang, a type of fermented soybean paste, can reduce blood sugar levels in people with prediabetes.
- Influenza. There is some evidence that taking a specific Panax ginseng extract (G115) by mouth beginning 4 weeks before a flu shot and continuing for 8 weeks after can decrease the risk of getting the flu.
- Memory. Taking a specific Panax ginseng extract (G115) together with vitamins, minerals and dimethylaminoethanol bitartrate might improve memory in older people with memory problems.
- Postmenopausal conditions. Some early research suggests that Panax ginseng might improve quality of life and menopausal symptoms, such as fatigue, insomnia, and depression in postmenopausal women. However, Panax ginseng does not appear to reduce hot flashes.
- Quality of life. While some research suggests that Panax ginseng might improve quality of life, other research shows no benefit.
- Wrinkled skin. Early research shows that taking a combination of Korean red ginseng root with Torilus fructus and Corni fructus daily for 24 weeks might reduce wrinkles, but does not appear to affect skin moisture, elasticity, thickness, or color.
- Fluid retention.
- Stomach inflammation and other digestive problems.
- Chronic fatigue syndrome (CFS) .
- Other conditions.
More evidence is needed to rate Panax ginseng for these uses.
Panax ginseng contains many active substances. The substances thought to be most important are called ginsenosides or panaxosides. Ginsenosides is the term coined by Asian researchers, and the term panaxosides was chosen by early Russian researchers.
Panax ginseng is often referred to as a general well-being medication, because it affects many different systems of the body.
Panax ginseng is POSSIBLY SAFE when taken by mouth and when applied to the skin as part of a multi-ingredient product (SS Cream), in the short-term. Panax ginseng is POSSIBLY UNSAFE when taken by mouth, long-term (more than 6 months). Researchers think it may have some hormone-like effects that could be harmful with prolonged use.
The most common side effect is trouble sleeping (insomnia). Less commonly, people experience menstrual problems, breast pain, increased heart rate, high or low blood pressure, headache, loss of appetite, diarrhea, itching, rash, dizziness, mood changes, vaginal bleeding, and other side effects.
Uncommon side effects that have been reported include severe rash called Stevens-Johnson syndrome, liver damage, and severe allergic reactions.
Special precautions & warnings:
Pregnancy and breast-feeding: Panax ginseng is POSSIBLY UNSAFE when taking by mouth during pregnancy. One of the chemicals in Panax ginseng has been found to cause birth defects in animals. Do not use Panax ginseng if you are pregnant.
Not enough is known about the safety of Panax ginseng during breast-feeding. Stay on the safe side and don’t use it.
Infants and children: Panax ginseng is LIKELY UNSAFE in infants and children. Using Panax ginseng in babies has been linked to poisoning that can be fatal. The safety of Panax ginseng in older children is not known. Until more is known, do not use Panax ginseng even in older children.
“Auto-immune diseases” such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), or other conditions: Panax ginseng seems to increase the activity of the immune system. It might make auto-immune diseases worse. Don’t use Panax ginseng if you have any auto-immune condition.
Bleeding conditions: Panax ginseng seems to interfere with blood clotting. Don’t use Panax ginseng if you have a bleeding condition.
Heart conditions: Panax ginseng can affect heart rhythm and blood pressure slightly on the first day it is used. However, there are usually no changes with continued use. Nevertheless, Panax ginseng has not been studied in people with cardiovascular disease. Use Panax ginseng with caution if you have heart disease.
Diabetes: Panax ginseng might lower blood sugar. In people with diabetes who are taking medications to lower blood sugar, adding Panax ginseng might lower blood sugar too much. Monitor your blood sugar closely if you have diabetes and use Panax ginseng.
Hormone-sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Panax ginseng contains chemicals (ginsenosides) that can act like estrogen. If you have any condition that might be made worse by exposure to estrogen, don’t use Panax ginseng.
Trouble sleeping (insomnia): High doses of Panax ginseng have been linked with insomnia. If you have trouble sleeping, use Panax ginseng with caution.
Schizophrenia (a mental disorder): High doses of Panax ginseng have been linked with sleep problems and agitation in people with schizophrenia. Be careful when using Panax ginseng if you have schizophrenia.
Organ transplant: Panax ginseng might make the immune system more active. This could interfere with the effectiveness of medications that are given after an organ transplant to reduce the chance that the organ will be rejected. If you have received an organ transplant, don’t use Panax ginseng.
Be cautious with this combination.
The body breaks down alcohol to get rid of it. Taking Panax ginseng might increase how fast your body gets rid of alcohol.
Caffeine can speed up the nervous system. By speeding up the nervous system, caffeine can make you feel jittery and speed up your heartbeat. Panax ginseng might also speed up the nervous system. Taking Panax ginseng along with caffeine might cause serious problems, including increased heart rate and high blood pressure. Avoid taking caffeine along with Panax ginseng.
Panax ginseng might have some of the same effects as estrogen. However, Panax ginseng is not as strong as estrogen pills. Taking Panax ginseng along with estrogen pills might decrease the effects of estrogen pills.
Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.
Some scientists think that Panax ginseng might decrease how well furosemide (Lasix) works. But there isn't enough information to know if this is a big concern.
Panax ginseng might decrease blood sugar. Insulin is also used to decrease blood sugar. Taking Panax ginseng along with insulin might cause your blood sugar to be too low. Monitor your blood sugar closely. The dose of your insulin might need to be changed.
Medications changed by the liver (Cytochrome P450 2D6 (CYP2D6) substrates)
Some medications are changed and broken down by the liver. Panax ginseng might decrease how quickly the liver breaks down some medications. Taking Panax ginseng along with some medications that are changed by the liver can increase the effects and side effects of your medication. Before taking Panax ginseng, talk to your healthcare provider if you take any medications that are changed by the liver.
Some medications that are changed by the liver include amitriptyline (Elavil), clozapine (Clozaril), codeine, desipramine (Norpramin), donepezil (Aricept), fentanyl (Duragesic), flecainide (Tambocor), fluoxetine (Prozac), meperidine (Demerol), methadone (Dolophine), metoprolol (Lopressor, Toprol XL), olanzapine (Zyprexa), ondansetron (Zofran), tramadol (Ultram), trazodone (Desyrel), and others.
Medications for depression (MAOIs)
Panax ginseng might stimulate the body. Some medications used for depression can also stimulate the body. Taking Panax ginseng with these medications used for depression might cause too much stimulation. This might cause side effects such as anxiousness, headache, restlessness, and insomnia.
Some of these medications used for depression include phenelzine (Nardil), tranylcypromine (Parnate), and others.
Medications for diabetes (Antidiabetes drugs)
Panax ginseng might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking Panax ginseng along with diabetes medications could add to the effects of diabetic medications and lower blood sugar too much. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.
Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
Medications that can cause an irregular heartbeat (QT interval-prolonging drugs)
Panax ginseng may cause an abnormal heartbeat when taken short-term. Taking Panax ginseng with drugs that can cause an irregular heartbeat might cause serious side effects, including heart rhythm problems (arrhythmias).
Some medications that affect the heartbeat include amiodarone (Cordarone), disopyramide (Norpace), dofetilide (Tikosyn), ibutilide (Corvert), procainamide (Pronestyl), quinidine, sotalol (Betapace), thioridazine (Mellaril), and many others.
Medications that decrease the immune system (Immunosuppressants)
Panax ginseng increases the immune system. By increasing the immune system, Panax ginseng might decrease the effectiveness of medications that decrease the immune system.
Some medications that decrease the immune system include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)
Panax ginseng might slow blood clotting. Taking Panax ginseng along with medications that also slow clotting might increase the chances of bruising and bleeding.
Some medications that slow blood clotting include aspirin, cilostazol (Pletal), clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.
Panax ginseng might affect how much nifedipine is available in the body. Taking Panax ginseng along with nifedipine might increase the blood pressure lowering effects of nifedipine.
Raltegravir is a drug used to treat people with HIV. Raltegravir has been associated with liver toxicity in some people. Taking Panax ginseng with raltegravir might increase the risk of liver toxicity in some people taking raltegravir.
Stimulant drugs speed up the nervous system. By speeding up the nervous system, stimulant medications can make you feel jittery and speed up your heartbeat. Panax ginseng might also speed up the nervous system. Taking Panax ginseng along with stimulant drugs might cause serious problems including increased heart rate and high blood pressure. Avoid taking stimulant drugs along with Panax ginseng.
Some stimulant drugs include diethylpropion (Tenuate), epinephrine, phentermine (Ionamin), pseudoephedrine (Sudafed), and many others.
Warfarin (Coumadin) is used to slow blood clotting. There is some concern that Panax ginseng might decrease the effectiveness of warfarin (Coumadin). But it's not clear if this interaction is a big problem. Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed.
Be watchful with this combination.
Fexofenadine is taken to treat seasonal allergies. When taken together with fexofenadine, Panax ginseng might reduce how much fexofenadine is available in the body. However, there isn't enough information to know if this is a big concern.
Medications changed by the liver (Cytochrome P450 1A1 (CYP1A1) substrates)
Some medications are changed and broken down by the liver. Panax ginseng might increase how quickly the liver breaks down some medications. Taking Panax ginseng along with some medications that are changed by the liver can decrease the effects and side effects of your medication. Before taking Panax ginseng, talk to your healthcare provider if you take any medications that are changed by the liver.
Some medications that are changed by the liver include chlorzoxazone, theophylline, and bufuralol.
Taking Panax ginseng along with bitter orange might increase the risk of the type of irregular heart rhythm, which can be life-threatening.
Country mallow contains ephedra. Ephedra can make the heart beat irregularly. Taking Panax ginseng along with country mallow might increase the risk of irregular heartbeats, which can be life-threatening.
Ephedra can make the heart beat irregularly. Taking Panax ginseng along with ephedra might increase the risk of irregular heartbeats, which can be life-threatening.
Herbs and supplements that lower blood sugar
Panax ginseng might lower blood sugar. Taking Panax ginseng along with other herbs and supplements that lower blood sugar might make the blood sugar too low. Some of these products include bitter melon, ginger, goat's rue, fenugreek, kudzu, willow bark, and others.
Herbs and supplements that might slow blood clotting
Using Panax ginseng with other herbs that can slow blood clotting might increase the risk of bleeding in some people. These other herbs include angelica, clove, danshen, ginger, ginkgo, red clover, turmeric, vitamin E, willow, and others.
The body breaks down alcohol to get rid of it. Taking Panax ginseng might increase how fast your body gets rid of alcohol.
Coffee and tea contain caffeine. Caffeine can speed up the nervous system. By speeding up the nervous system, caffeine can make you feel jittery and speed up your heartbeat. Panax ginseng might also speed up the nervous system. Taking Panax ginseng along with caffeine might cause serious problems including increased heart rate and high blood pressure. Avoid taking caffeine along with Panax ginseng.
The following doses have been studied in scientific research:
APPLIED TO THE SKIN:
- For treating type 2 diabetes: 200 mg daily.
- For erectile dysfunction: Panax ginseng 900 mg three times daily.
- For premature ejaculation: a cream (SS-Cream) containing Panax ginseng and other ingredients has been applied to the glans penis one hour before intercourse and washed off before intercourse.
Asian Ginseng, Asiatic Ginseng, Chinese Ginseng, Chinese Red Ginseng, Ginseng, Ginseng Asiatique, Ginseng Blanc, Ginseng Blanc de Corée, Ginseng Chinois, Ginseng Coréen, Ginseng Coréen Rouge, Ginseng de Corée, Ginseng Japonais, Ginseng Oriental, Ginseng Panax, Ginseng Radix Alba, Ginseng Root, Ginseng Rouge, Ginseng Sino-coréen, Ginseng Tibétain, Guigai, Hong Shen, Japanese Ginseng, Jen-Shen, Jinsao, Jintsam, Insam, Korean Ginseng, Korean Ginseng Root, Korean Panax, Korean Panax Ginseng, Korean Red Ginseng, Korean White Ginseng, Mandragore de Chine, Ninjin, Ninzin, Oriental Ginseng, Panax Coréen, Panax Ginseng Blanc, Panax schinseng, Racine de Vie, Radix Ginseng Rubra, Red Chinese Ginseng, Red Ginseng, Red Kirin Ginseng, Red Korean Ginseng, Red Panax Ginseng, Ren Shen, Renshen, Renxian, Sang, Seng, Sheng Shai Shen, Tibetan Ginseng, White Ginseng, White Panax Ginseng.
To learn more about how this article was written, please see the Natural Medicines Comprehensive Database methodology.methodology (http://www.nlm.nih.gov/medlineplus/druginfo/natural/methodology.html).
To see all references for the Ginseng, Panax page, please go to http://www.nlm.nih.gov/medlineplus/druginfo/natural/1000.html.
- Kennedy DO, Scholey AB, and Wesnes KA. Differential, dose dependent changes in cognitive performance following acute administration of a Ginkgo biloba/Panax ginseng combination to healthy young volunteers. Nutr.Neurosci. 2001;4:399-412. View abstract.
Wesnes KA, Faleni RA, Hefting NR, and et al. The cognitive, subjective, and physical effects of a Ginkgo biloba/Panax ginseng combination in healthy volunteers with neurasthenic complaints. Psychopharmacol Bull 1997;33:677-683. View abstract.
- Hartley, D. E., Elsabagh, S., and File, S. E. Gincosan (a combination of Ginkgo biloba and Panax ginseng): the effects on mood and cognition of 6 and 12 weeks' treatment in post-menopausal women. Nutr.Neurosci. 2004;7(5-6):325-333. View abstract.
- Kennedy, D. O., Haskell, C. F., Wesnes, K. A., and Scholey, A. B. Improved cognitive performance in human volunteers following administration of guarana (Paullinia cupana) extract: comparison and interaction with Panax ginseng. Pharmacol Biochem Behav 2004;79:401-411. View abstract.
- Gurley, B. J., Gardner, S. F., Hubbard, M. A., Williams, D. K., Gentry, W. B., Cui, Y., and Ang, C. Y. Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: St John's wort, garlic oil, Panax ginseng and Ginkgo biloba. Drugs Aging 2005;22:525-539. View abstract.
- Ito, T. Y., Trant, A. S., and Polan, M. L. A double-blind placebo-controlled study of ArginMax, a nutritional supplement for enhancement of female sexual function. J Sex Marital Ther 2001;27:541-549. View abstract.
- Niederhofer, H. Panax ginseng may improve some symptoms of attention-deficit hyperactivity disorder. Journal of Dietary Supplements 2009;6:22-27.
- Liu, P., Xu, Y., Yin, H., Wang, J., Chen, K., and Li, Y. Developmental toxicity research of ginsenoside Rb1 using a whole mouse embryo culture model. Birth Defects Res B Dev Reprod Toxicol 2005;74:207-209. View abstract.
- Liu, P., Yin, H., Xu, Y., Zhang, Z., Chen, K., and Li, Y. Effects of ginsenoside Rg1 on postimplantation rat and mouse embryos cultured in vitro. Toxicol In Vitro 2006;20:234-238. View abstract.
- Lee, Y. H., Lee, B. K., Choi, Y. J., Yoon, I. K., Chang, B. C., and Gwak, H. S. Interaction between warfarin and Korean red ginseng in patients with cardiac valve replacement. Int J Cardiol. 11-19-2010;145:275-276. View abstract.
Hao, M., Ba, Q., Yin, J., Li, J., Zhao, Y., and Wang, H. Deglycosylated ginsenosides are pG2 cells than glycosylated ginsenosides. Drug Metab Pharmacokinet. 12-17-2010. View abstract.
- Zhang, R., Jie, J., Zhou, Y., Cao, Z., and Li, W. Long-term effects of Panax ginseng on disposition of fexofenadine in rats in vivo. Am J Chin Med 2009;37:657-667. View abstract.
- Hu, Z., Yang, X., Ho, P. C., Chan, S. Y., Heng, P. W., Chan, E., Duan, W., Koh, H. L., and Zhou, S. Herb-drug interactions: a literature review. Drugs 2005;65:1239-1282. View abstract.
- Engels, H. J., Fahlman, M. M., and Wirth, J. C. Effects of ginseng on secretory IgA, performance, and recovery from interval exercise. Med Sci Sports Exerc 2003;35:690-696. View abstract.
- Kulaputana, O., Thanakomsirichot, S., and Anomasiri, W. Ginseng supplementation does not change lactate threshold and physical performances in physically active Thai men. J Med Assoc Thai. 2007;90:1172-1179. View abstract.
- Cho, S., Won, C. H., Lee, D. H., Lee, M. J., Lee, S., So, S. H., Lee, S. K., Koo, B. S., Kim, N. M., and Chung, J. H. Red ginseng root extract mixed with Torilus fructus and Corni fructus improves facial wrinkles and increases type I procollagen synthesis in human skin: a randomized, double-blind, placebo-controlled study. J Med Food 2009;12:1252-1259. View abstract.
- Wiklund I, Karlberg J, and Lund B. A double bind comparison of the effect on quality of life of a combination of vital substances including standarized ginseng G115 and placebo. Curr Ther Res 1994;55:32-42.
- Kim, J. H., Park, C. Y., and Lee, S. J. Effects of sun ginseng on subjective quality of life in cancer patients: a double-blind, placebo-controlled pilot trial. J Clin Pharm Ther 2006;31:331-334. View abstract.
- Ni, H. X., Yu, N. J., and Yang, X. H. The study of ginsenoside on PPARgamma expression of mononuclear macrophage in type 2 diabetes. Mol.Biol Rep. 2010;37:2975-2979. View abstract.
- Shin, S. K., Kwon, J. H., Jeong, Y. J., Jeon, S. M., Choi, J. Y., and Choi, M. S. Supplementation of cheonggukjang and red ginseng cheonggukjang can improve plasma lipid profile and fasting blood glucose concentration in subjects with impaired fasting glucose. J Med Food 2011;14(1-2):108-113. View abstract.
- Kim, S., Shin, B. C., Lee, M. S., Lee, H., and Ernst, E. Red ginseng for type 2 diabetes mellitus: a systematic review of randomized controlled trials. Chin J Integr.Med 2011;17:937-944. View abstract.
- Kim, T. H., Jeon, S. H., Hahn, E. J., Paek, K. Y., Park, J. K., Youn, N. Y., and Lee, H. L. Effects of tissue-cultured mountain ginseng (Panax ginseng CA Meyer) extract on male patients with erectile dysfunction. Asian J Androl 2009;11:356-361. View abstract.
- Jang, D. J., Lee, M. S., Shin, B. C., Lee, Y. C., and Ernst, E. Red ginseng for treating erectile dysfunction: a systematic review. Br.J Clin.Pharmacol. 2008;66:444-450. View abstract.
- Ito, T. Y., Polan, M. L., Whipple, B., and Trant, A. S. The enhancement of female sexual function with ArginMax, a nutritional supplement, among women differing in menopausal status. J Sex Marital Ther 2006;32:369-378. View abstract.
- Han, K. H., Choe, S. C., Kim, H. S., Sohn, D. W., Nam, K. Y., Oh, B. H., Lee, M. M., Park, Y. B., Choi, Y. S., Seo, J. D., and Lee, Y. W. Effect of red ginseng on blood pressure in patients with essential hypertension and white coat hypertension. Am J Chin Med 1998;26:199-209. View abstract.
- Dharmananda S. Panax ginseng: a clinical study of its effects on risk factors of cardiovascular diseases. Bulletin of the Oriental Healing Arts Institute 1983;8:1-13.
- Oh, K. J., Chae, M. J., Lee, H. S., Hong, H. D., and Park, K. Effects of Korean red ginseng on sexual arousal in menopausal women: placebo-controlled, double-blind crossover clinical study. J Sex Med 2010;7(4 Pt 1):1469-1477. View abstract.
- Sievenpiper, J. L., Sung, M. K., Di Buono, M., Seung-Lee, K., Nam, K. Y., Arnason, J. T., Leiter, L. A., and Vuksan, V. Korean red ginseng rootlets decrease acute postprandial glycemia: results from sequential preparation- and dose-finding studies. J Am Coll.Nutr 2006;25:100-107. View abstract.
- Reay, J. L., Scholey, A. B., Milne, A., Fenwick, J., and Kennedy, D. O. Panax ginseng has no effect on indices of glucose regulation following acute or chronic ingestion in healthy volunteers. Br J Nutr 2009;101:1673-1678. View abstract.
- Vuksan, V., Sung, M. K., Sievenpiper, J. L., Stavro, P. M., Jenkins, A. L., Di, Buono M., Lee, K. S., Leiter, L. A., Nam, K. Y., Arnason, J. T., Choi, M., and Naeem, A. Korean red ginseng (Panax ginseng) improves glucose and insulin regulation in well-controlled, type 2 diabetes: results of a randomized, double-blind, placebo-controlled study of efficacy and safety. Nutr Metab Cardiovasc.Dis 2008;18:46-56. View abstract.
- Reay, J. L., Kennedy, D. O., and Scholey, A. B. The glycaemic effects of single doses of Panax ginseng in young healthy volunteers. Br J Nutr 2006;96:639-642. View abstract.
- Sung, H., Jung, Y. S., and Cho, Y. K. Beneficial effects of a combination of Korean red ginseng and highly active antiretroviral therapy in human immunodeficiency virus type 1-infected patients. Clin Vaccine Immunol. 2009;16:1127-1131. View abstract.
- Lee, J. S., Kwon, K. A., Jung, H. S., Kim, J. H., and Hahm, K. B. Korea red ginseng on Helicobacter pylori-induced halitosis: newer therapeutic strategy and a plausible mechanism. Digestion 2009;80:192-199. View abstract.
- Le Gal M, Cathebras P, and Struby K. Pharmaton capsules in the treatment of functional fatigue. A double-blind study versus placebo evaluated by a new methodology. Phytotherapy Research 1996;10:49-53.
- Yun, T. K., Zheng, S., Choi, S. Y., Cai, S. R., Lee, Y. S., Liu, X. Y., Cho, K. J., and Park, K. Y. Non-organ-specific preventive effect of long-term administration of Korean red ginseng extract on incidence of human cancers. J Med Food 2010;13:489-494. View abstract.
- Mateo-Carrasco, H., Galvez-Contreras, M. C., Fernandez-Gines, F. D., and Nguyen, T. V. Elevated liver enzymes resulting from an interaction between Raltegravir and Panax ginseng: a case report and brief review. Drug Metabol.Drug Interact. 2012;27:171-175. View abstract.
- Kwon, K. R., Kim, H., Kim, J. S., Yoo, H. S., and Cho, C. K. Case series of non-small cell lung cancer treated with mountain Ginseng pharmacopuncture. J Acupunct.Meridian.Stud. 2011;4:61-68. View abstract.
- Lee, J. H., Kwon, K. R., Cho, C. K., Han, S. S., and Yoo, H. S. Advanced cancer cases treated with cultivated wild ginseng phamacopuncture. J Acupunct.Meridian.Stud. 2010;3:119-124. View abstract.
- Lee, S. T., Chu, K., Sim, J. Y., Heo, J. H., and Kim, M. Panax ginseng enhances cognitive performance in Alzheimer disease. Alzheimer Dis.Assoc.Disord. 2008;22:222-226. View abstract.
- Heo, J. H., Lee, S. T., Chu, K., Oh, M. J., Park, H. J., Shim, J. Y., and Kim, M. An open-label trial of Korean red ginseng as an adjuvant treatment for cognitive impairment in patients with Alzheimer's disease. Eur.J Neurol. 2008;15:865-868. View abstract.
- Reay, J. L., Kennedy, D. O., and Scholey, A. B. Effects of Panax ginseng, consumed with and without glucose, on blood glucose levels and cognitive performance during sustained 'mentally demanding' tasks. J Psychopharmacol. 2006;20:771-781. View abstract.
- Reay, J. L., Kennedy, D. O., and Scholey, A. B. Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity. J Psychopharmacol. 2005;19:357-365. View abstract.
- Neri, M., Andermarcher, E., Pradelli, J. M., and Salvioli, G. Influence of a double blind pharmacological trial on two domains of well-being in subjects with age associated memory impairment. Arch Gerontol.Geriatr. 1995;21:241-252. View abstract.
- Forgo, I., Kayasseh, L., and Staub, J. J. [Effect of a standardized ginseng extract on general well-being, reaction time, lung function and gonadal hormones]. Med Welt 5-8-1981;32:751-756. View abstract.
- Reay, J. L., Scholey, A. B., and Kennedy, D. O. Panax ginseng (G115) improves aspects of working memory performance and subjective ratings of calmness in healthy young adults. Hum Psychopharmacol. 2010;25:462-471. View abstract.
- Smith M, Lin KM, and Zheng YP. PIII-89 an open trial of nifedipine-herb interactions: Nifedipine with St. John's wort, ginseng or ginkgo biloba. Clin Pharm Ther 2001;69:P86.
- An X, Zhang AL, Yang AW, et al. Oral ginseng formulae for chronic obstructive pulmonary disease: a systematic review. Resp Med 2011;105:165-76. View abstract.
- Reeds DN, Patterson BW, Okunade A, et al. Ginseng and ginsenoside re do not improve beta-cell function or insulin sensitivity in overweight and obese subjects with impaired glucose tolerance or diabetes. Diabetes Care 2011;34:1071-6. View abstract.
- Lee SH, Ahn YM, Ahn SY, et al. Interaction between warfarin and Panax ginseng in ischemic stroke patients. J Altern Complement Med 2008;14:715-721. View abstract.
- Dasgupta A, Tso G, Wells A. Effect of Asian ginseng, Siberian ginseng, and Indian ayurvedic medicine Ashwagandha on serum digoxin measurement by Digoxin III, a new digoxin immunoassay. J Clin Lab Anal 2008;22:295-301. View abstract.
- Chow L, Johnson M, Wells A, Dasgupta A. Effect of the traditional Chinese medicines Chan Su, Lu-Shen-Wan, Dan Shen, and Asian ginseng on serum digoxin measurement by Tina-quant (Roche) and Synchron LX system (Beckman) digoxin immunoassays. J Clin Lab Anal 2003;17:22-7. View abstract.
- Dasgupta A, Wu S, Actor J, et al. Effect of Asian and Siberian ginseng on serum digoxin measurement by five digoxin immunoassays. Significant variation in digoxin-like immunoreactivity among commercial ginsengs. Am J Clin Pathol 2003;119:298-303. View abstract.
- Jiang X, Blair EY, McLachlan AJ. Investigation of the effects of herbal medicines on warfarin response in healthy subjects: a population pharmacokinetic-pharmacodynamic modeling approach. J Clin Pharmacol 2006;46:1370-8. View abstract.
- Cui Y, Shu XO, Gao YT, et al. Association of ginseng use with survival and quality of life among breast cancer patients. Am J Epidemiol 2006;163:645-53. View abstract.
- Kabalak AA, Soyal OB, Urfalioglu A, et al. Menometrorrhagia and tachyarrhythmia after using oral and topical ginseng. J Womens Health (Larchmt) 2004;13:830-3. View abstract.
- Kim SH, Park KS. Effects of Panax ginseng extract on lipid metabolism in humans. Pharmacol Res 2003;48:511-3. View abstract.
- Cho J, Park W, Lee S, et al. Ginsenoside-Rb1 from Panax ginseng C.A. Meyer activates estrogen receptor-alpha and -beta, independent of ligand binding. J Clin Endocrinol Metab 2004;89:3510-5. View abstract.
- Sievenpiper JL, Arnason JT, Leiter LA, Vuksan V. Decreasing, null and increasing effects of eight popular types of ginseng on acute postprandial glycemic indices in healthy humans: the role of ginsenosides. J Am Coll Nutr 2004;23:248-58. View abstract.
- Lee FC, Ko JH, Park JK, Lee JS. Effects of Panax ginseng on blood alcohol clearance in man. Clin Exp Pharmacol Physiol 1987;14:543-6. View abstract.
- Wiwanikit V, Taungjarwinai W. A case report of suspected ginseng allergy. Medscape General Medicine 6 , 2004. Available at: www.medscape.com/viewarticle/482833 (Accessed 17 September 2004).
- Yun YP, Do JH, Ko SR, et al. Effects of Korean red ginseng and its mixed prescription on the high molecular weight dextran-induced blood stasis in rats and human platelet aggregation. J Ethnopharmacol 2001;77:259-64. View abstract.
- Jiang X, Williams KM, Liauw WS, et al. Effect of St John's wort and ginseng on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. Br J Clin Pharmacol 2004;57:592-9. View abstract.
- McBride BF, Karapanos AK, Krudysz A, et al. Electrocardiographic and hemodynamic effects of a multicomponent dietary supplement containing ephedra and caffeine: a randomized controlled trial. JAMA 2004;291:216-21. View abstract.
- Xu QF, Fang XL, Chen DF. Pharmacokinetics and bioavailability of ginsenoside Rb1 and Rg1 from Panax notoginseng in rats. J Ethnopharmacol 2003;84:187-92. View abstract.
- Tamaoki J, Nakata J, Kawatani K, et al. Ginsenoside-induced relaxation of human bronchial smooth muscle via release of nitric oxide. Br J Pharmacol 2000;130:1859-64.. View abstract.
- Keum YS, Park KK, Lee JM, et al. Antioxidant and anti-tumor promoting activities of the methanol extract of heat-processed ginseng. Cancer Lett 2000;150:41-8.. View abstract.
- Moon J, Yu SJ, Kim HS, Sohn J. Induction of G cell cycle arrest and p27(KIP1) increase by panaxydol isolated from Panax ginseng. Biochem Pharmacol 2000;59:1109-16.. View abstract.
- Lee YJ, Jin YR, Lim WC, et al. Ginsenoside-Rb1 acts as a weak phytoestrogen in MCF-7 human breast cancer cells. Arch Pharm Res 2003;26:58-63.. View abstract.
- Punnonen R, Lukola A. Oestrogen-like effect of ginseng. Br Med J 1980;281:1110.. View abstract.
- Hammond TG, Whitworth JA. Adverse reactions to ginseng [letter]. Med J Aust 1981;1:492.. View abstract.
- Wiklund IK, Mattsson LA, Lindgren R, et al. Effects of a standardized ginseng extract on quality of life and physiological parameters in symptomatic postmenopausal women: a double-blind, placebo-controlled trial. Int J Clin Pharmacol Res 1999;19:89-99.. View abstract.
- Gurley BJ, Gardner SF, Hubbard MA, et al. Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans. Clin Pharmacol Ther 2002;72:276-87.. View abstract.
- Chan LY, Chiu PY, Lau TK. An in-vitro study of ginsenoside Rb-induced teratogenicity using a whole rat embryo culture model. Hum Reprod 2003;18:2166-8.. View abstract.
- Cardinal BJ, Engels HJ. Ginseng does not enhance psychological well-being in healthy, young adults: results of a double-blind, placebo-controlled, randomized clinical trial. J Am Diet Assoc 2001;101:655-60.. View abstract.
- Suzuki H, Rhim JH. Effect of samgyetang feeding on plasma lipids, glucose, glycosylated hemoglobin, and stress-induced gastric ulcers in mice. Nutr Res 2000;20:575-84.
- Wesnes KA, Ward T, McGinty A, Petrini O. The memory enhancing effects of a Ginkgo biloba/Panax ginseng combination in healthy middle-aged volunteers. Psychopharmacology (Berl) 2000;152:353-61.. View abstract.
- Scaglione F, Weiser K, Alessandria M. Effects of the standardized ginseng extract G115 (Reg.) in patients with chronic bronchitis: A nonblinded, randomized, comparative pilot study. Clin Drug Invest 2001;21:41-5.
- Hong B, Ji YH, Hong JH, et al. A double-blind crossover study evaluating the efficacy of Korean red ginseng in patients with erectile dysfunction: a preliminary report. J Urol 2002;168:2070-3.. View abstract.
- Pan SJ, Ding Z, Ivy JL. Ginseng's effects on glucose tolerance and mRNA profiles in a animal model of Type II diabetes. Altern Ther 2001;7:S26.
- Cheng TO. Panax (ginseng) is not a panacea. Arch Intern Med 2000;160:3329. View abstract.
- Ng TB, Wang H. Panaxagin, a new protein from Chinese ginseng possesses anti-fungal, anti-viral, translation-inhibiting and ribonuclease activities. Life Sci 2001;68:739-49. View abstract.
- Kim YK, Guo Q, Packer L. Free radical scavenging activity of red ginseng aqueous extracts. Toxicology 2002;172:149-56. View abstract.
- Ellis JM, Reddy P. Effects of Panax ginseng on quality of life. Ann Pharmacother 2002;36:375-9. View abstract.
- Dharmananda S. The nature of ginseng: traditional use, modern use, and the question of dosage. Herbalgram 2002;54:34-51.
- Scholey AB, Kennedy DO. Acute, dose-dependent cognitive effects of Ginkgo biloba, Panax ginseng and their combination in healthy young volunteers: differential interactions with cognitive demand. Hum Psychopharmacol 2002;17:35-44.. View abstract.
- Vuksan V, Stavro MP, Sievenpiper JL, et al. Similar postprandial glycemic reductions with escalation of dose and administration time of American ginseng in type 2 diabetes. Diabetes Care 2000;23:1221-6. View abstract.
- Caso MA, Vargas RR, Salas VA, Begona IC. Double-blind study of a multivitamin complex supplemented with ginseng extract. Drugs Exp Clin Res 1996;22:323-9. View abstract.
- Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
- Caron MF, Hotsko AL, Robertson S, et al. Electrocardiographic and hemodynamic effects of Panax ginseng. Ann Pharmacother 2002;36:758-63.. View abstract.
- Ding DZ, Shen TK, Cui YZ. Effects of red ginseng on the congestive heart failure and its mechanism. Chung Kuo Chung His I Chieh Ho Tsa Chih 1995;15:325-7. View abstract.
- Engels HJ, Wirth JC. No ergogenic effects of ginseng (Panax ginseng C.A. Meyer) during grades maximal aerobic exercise. J Am Diet Assoc 1997;97:1110-5. View abstract.
- Allen JD, McLung J, Nelson AG, Welsch M. Ginseng supplementation does not enhance healthy young adults' peak aerobic exercise performance. J Am Coll Nutr 1998;17:462-6. View abstract.
- Lee BM, Lee SK, Kim HS. Inhibition of oxidative DNA damage, 8-OHdG, and carbonyl contents in smokers treated with antioxidants (vitamin E, vitamin C, beta-carotene and red ginseng.) Cancer Lett 1998;132:219-27. View abstract.
- Sotaniemi EA, Haapakoski E, Rautio A. Ginseng therapy in non-insulin-dependent diabetic patients. Diabetes Care 1995;18:1373-5. View abstract.
- Tode T, Kikuchi Y, Hirata J, et al. Effect of Korean red ginseng on psychological functions in patients with severe climacteric syndromes. Int J Gynaecol Obstet 1999;67:169-74. View abstract.
- Palop-Larrea V, Gonzalvez-Perales JL, Catalan-Oliver C, et al. Metrorrhagia and ginseng. Ann Pharmacother 2000;34:1347-8. View abstract.
- Siegel RK. Ginseng Abuse Syndrome. JAMA 1979;241:1614-5.
- Kase Y, Saitoh K, Ishige A, et al. Mechanisms by which Hange-shashin-to reduces prostaglandin E2 levels. Biol Pharm Bull 1998;21:1277-81. View abstract.
- Hiai S, Yokoyama H, Oura H, et al. Stimulation of pituitary-adrenocortical system by ginseng saponin. Endocrinol Jpn 1979;26:661-5. View abstract.
- Shin HR, Kim JY, Yun TK, et al. The cancer-preventive potential of Panax ginseng: a review of human and experimental evidence. Cancer Causes Control 2000;11:565-76. View abstract.
- Belogortseva NI, Yoon JY, Kim KH. Inhibition of Helicobacter pylori hemagglutination by polysaccharide fractions from roots of Panax ginseng. Planta Med 2000;66:217-20. View abstract.
- Lewis R, Wake G, Court G, et al. Non-ginsenoside nicotinic activity in ginseng species. Phytother Res 1999;13;59-64. View abstract.
- Song Z, Kharazmi A, Wu H, et al. Effects of Ginseng treatment on neutrophil chemiluminescence and immunoglobulin G subclasses in a rat model of chronic Pseudomonas aeruginosa pneumonia. Clin Diagn Lab Immunol 1998;5:882-7. View abstract.
- Song Z, Johansen HK, Faber V, et al. Ginseng treatment reduces bacterial load and lung pathology in chronic Pseudomonas aeruginosa pneumonia in rats. Antimicrob Agents Chemother 1997;41:961-4. View abstract.
- Choi HK, Jung GW, Moon KH, et al. Clinical study of SS-Cream in patients with lifelong premature ejaculation. Urology 2000;55:257-61. View abstract.
- Zhu M, Chan KW, Ng LS, et al. Possible influences of ginseng on the pharmacodynamics of warfarin in rats. J Pharm Pharmacol 1999;51:175-80. View abstract.
- Sorensen H, Sonne J. A double-masked study of the effects of ginseng on cognitive functions. Curr Ther Res 1996;57:959-68.
- Yun TK, Choi SY. Non-organ specific cancer prevention of ginseng: a prospective study in Korea. Int J Epidemiol 1998;27:359-64. View abstract.
- Park HJ, Lee JH, Song YB, Park KH. Effects of dietary supplementation of lipophilic fraction from Panax ginseng on cGMP and cAMP in rat platelets and on blood coagulation. Biol Pharm Bull 1996;19:1434-9. View abstract.
- Vogler BK, Pittler MH, Ernst E. The efficacy of ginseng. A systemic review of randomized clinical trials. Eur J Clin Pharmacol 1999;55:567-75. View abstract.
- Gurley BJ, Gardner SF, Hubbard MA. Clinical assessment of potential cytochrome P450-mediated herb-drug interactions. AAPS Ann Mtg & Expo Indianapolis, IN: 2000; Oct 29 - Nov 2:presentation #3460.
- Becker BN. Ginseng-induced diuretic resistance. JAMA 1996;276:606-7. View abstract.
- Janetzky K, Morreale AP. Probable interaction between warfarin and ginseng. Am J Health Syst Pharm 1997;54:692-3. View abstract.
- Jones BD, Runikis AM. Interaction of ginseng with phenelzine. J Clin Psychopharmacol 1987;7:201-2. View abstract.
- Shader RI, Greenblatt DJ. Phenelzine and the dream machine-ramblings and reflections. J Clin Psychopharmacol 1985;5:65. View abstract.
- Hamid S, Rojter S, Vierling J. Protracted cholestatic hepatitis after the use of Prostata. Ann Intern Med 1997;127:169-70. View abstract.
- Brown R. Potential interactions of herbal medicines with antipsychotics, antidepressants and hypnotics. Eur J Herbal Med 1997;3:25-8.
- Dega H, Laporte JL, Frances C, et al. Ginseng as a cause of Stevens-Johnson syndrome. Lancet 1996;347:1344. View abstract.
- Ryu S, Chien Y. Ginseng-associated cerebral arteritis. Neurology 1995;45:829-30. View abstract.
- Gonzalez-Seijo JC, Ramos YM, Lastra I. Manic episode and ginseng: Report of a possible case. J Clin Psychopharmacol 1995;15:447-8. View abstract.
- Greenspan EM. Ginseng and vaginal bleeding [letter]. JAMA 1983;249:2018. View abstract.
- Hopkins MP, Androff L, Benninghoff AS. Ginseng face cream and unexplained vaginal bleeding. Am J Obstet Gynecol 1988;159:1121-2. View abstract.
- Palmer BV, Montgomery AC, Monteiro JC, et al. Gin Seng and mastalgia [letter]. BMJ 1978;1:1284. View abstract.
- Scaglione F, Cattaneo G, Alessandria M, Cogo R. Efficacy and safety of the standardized Ginseng extract G115 for potentiating vaccination against the influenza syndrome and protection against the common cold. Drugs Exp Clin Res 1996;22:65-72. View abstract.
- Foster S, Tyler VE. Tyler's Honest Herbal, 4th ed., Binghamton, NY: Haworth Herbal Press, 1999.
- Robbers JE, Speedie MK, Tyler VE. Pharmacognosy and Pharmacobiotechnology. Baltimore, MD: Williams & Wilkins, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
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