In a person with Alzheimer's disease, neurofibrillary tangles and plaques develop causing both structural and chemical problems in the brain. Alzheimer's disease appears to disconnect areas of the brain that normally work together.
Update Date 9/26/2011
Updated by: Luc Jasmin, MD, PhD, Department of Neurosurgery at Cedars-Sinai Medical Center, Los Angeles, and Department of Anatomy at UCSF, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.