Acquired platelet function defects are conditions that prevent clotting elements in the blood called platelets from working as they should. The term "acquired" means these conditions are not present at birth.
With platelet disorders can affect the number of platelets, how well they function, or both. Any platelet disorder affects normal blood clotting.
Disorders that can cause problems in platelet function include:
Other causes include:
Treatment is aimed at the cause of the problem.
Most of the time, treating the cause of the problem corrects the defect.
Call your health care provider if:
Using medicines as directed can reduce the risk of drug-related acquired platelet function defects. Treating other disorders may also reduce the risk. Some cases cannot be prevented.
Acquired qualitative platelet disorders; Acquired disorders of platelet function
Diz-Kucukkaya R, Lopez JA, Acquired disorders of platelet function. In: Hoffman R, Benz EJ Jr, Silberstein LE, Heslop HE, Weitz JI, eds. Hematology: Basic Principles and Practice. 6th ed. Philadelphia, PA: Saunders Elsevier; 2012:chap 132.
Ragni MV. Hemorrhagic Disorders: Coagulation Factor Deficiencies. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 177.
Updated by: Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, Bethanne Black, Stephanie Slon, and Nissi Wang.
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