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Hemolytic anemia caused by chemicals and toxins

Hemolytic anemia caused by chemicals and toxins is a lack of red blood cells that occurs when red blood cells are excessively damaged by certain chemicals or toxins.

Causes

Possible substances that can cause hemolytic anemia include:

  • Anti-malaria drugs (quinine compounds)
  • Arsenic
  • Dapsone
  • Intravenous water infusion (not half-normal saline or normal saline)
  • Metals (chromium/chromates, platinum salts, nickel compounds, copper, lead, cis-platinum)
  • Nitrites
  • Nitrofurantoin
  • Penicillin
  • Phenazopyridine (Pyridium)
  • Rho immune globulin (WinRho)
  • Ribavirin
  • Snake bites (some snake venom contains hemolytic toxins)
  • Sulfonamides
  • Sulfones

This list is not all-inclusive.

Alternative Names

Anemia - hemolytic - caused by chemicals or toxins

References

Schwartz RS. Autoimmune and intravascular hemolytic anemias. In: Goldman L, Ausiello D, eds.Cecil Medicine

Schrier SL, Price EA. Extrinsic nonimmune hemolytic anemias. In: Hoffman R, Benz EJ, Shattil SS, et al., eds.Hematology: Basic Principles and Practice

Update Date 2/24/2014

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