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Orbital pseudotumor

Orbital pseudotumor is a swelling of the tissues behind the eye in an area called the orbit. The orbit is the bony cavity in the skull where the eye sits. It protects the eyeball and the muscles and tissue that surround it.

Unlike cancerous tumors, orbital pseudotumor does not spread to other tissues or places in the body.

Causes

The cause is unknown. It most commonly affects young women, although it can still occur at any age.

Symptoms

  • Pain in eye - may be severe
  • Restricted eye movement
  • Decreased vision
  • Double vision
  • Eye swelling (proptosos)
  • Red eye (rare)

Exams and Tests

Signs of pseudotumor can be seen when the eye is examined. Tests must be done to tell the difference between  pseudotumor and a cancerous tumor and eye problems that can occur in people with thyroid disease.

Tests may include:

Treatment

Mild cases may go away without treatment. More severe cases will usually respond to treatment with corticosteroids. Very severe cases may develop damaging pressure on the eye, and require surgical movement of the bones of the orbit to relieve pressure on the eyeball.

Outlook (Prognosis)

Most cases are mild and do well. Severe cases may be resistant to treatment and visual loss may occur. Orbital pseudotumor usually involves only one eye.

Possible Complications

Severe cases of orbital pseudotumor may push the eye forward to the extent that the lids can no longer protect the cornea, leading to drying of the affected eye. This can lead to damage to the clarity of the cornea, or to corneal ulcer (wound). The eye muscles may not be able to properly aim the eye, and double vision may result.

When to Contact a Medical Professional

Patients with pseudotumor will be closely followed by an ophthalmologist with experience in the treatment of orbital disease.

If you experience irritation of the cornea, redness, pain, or decreased vision, call your ophthalmologist or general health care provider right away.

Alternative Names

Idiopathic orbital inflammatory syndrome (IOIS)

References

Yanoff M, Cameron D. Diseases of the visual system. In: Goldman L, Schafer AI, eds.Cecil Medicine

Karesh JW, On AV, Hirschbein MJ. Noninfectious orbital inflammatory disease. In: Tasman W, Jaeger EA, eds.Duane’s Ophthalmology

Glaser JS, Tse DT, Chang WJ. Orbital disease and neuro-ophthalmology. In: Tasman W, Jaeger EA, eds.Duane’s Ophthalmology

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Update Date 9/3/2012

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