Urine immunofixation is a test to look for proteins in urine.
You will need to supply a clean-catch (midstream) urine sample.
For an infant:
I may take more than one try to get a sample from an infant. An active baby can move the bag, so that the urine goes into the diaper. Check the infant often and change the bag after the urine has been collected. Drain the urine from the bag into the container given to you by your health care provider.
Deliver the sample to the lab or your health care provider as soon as possible after it is done.
No special steps are necessary for this test.
The test involves only normal urination. There is no discomfort.
No presence of monoclonal immunoglobulins is normal.
The presence of monoclonal proteins may indicate:
Immunofixation is similar to urine immunoelectrophoresis, but it may give more rapid results.
McPherson RA, Massey HD. Laboratory Evaluation of Immunoglobulin Function and Humoral Immunity. In: Mcpherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods.22nd ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 46
McPherson RA and Pincus MR. Henry's Clinical Diagnosis and Management by Laboratory Methods.21st ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 46.
Hoffman R, Benz Jr. EJ, Shattil SJ, et al., eds. Hematology: Basic Principles and Practice. 4th ed. Philadelphia, Pa: Churchill Livingston; 2005:727-33.
Updated by: Todd Gersten, MD, Hematology/Oncology, Palm Beach Cancer Institute, West Palm Beach, FL. Review provided by VeriMed Healthcare Network.Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, Bethanne Black, Stephanie Slon, and Nissi Wang.
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