Gastric tissue biopsy is the removal of stomach tissue for examination. A culture is a laboratory test that examines the tissue sample for bacteria and other organisms that can cause disease.
The tissue sample is removed during a procedure called upper endoscopy (or EGD). It is done with a small camera (flexible endoscope) that is inserted down the throat into the stomach.
The health care provider sends the tissue sample to a laboratory where it is examined for signs of cancer, certain infections, or other problems.
Follow instructions on how to prepare for the procedure. You will likely be asked not to eat or drink anything for 6 to 12 hours before the procedure.
Your health care provider will tell you what to expect during the procedure.
This test may be done to diagnose a stomach ulcer or the cause of other stomach symptoms. These symptoms may include:
A gastric tissue biopsy and culture can help detect:
A gastric tissue biopsy is normal if it does not show cancer, other damage to the lining of the stomach, or signs of organisms that cause infection.
A gastric tissue culture may be considered normal if it does not show certain bacteria. Stomach acids normally prevent too much bacteria from growing.
Abnormal results may be due to:
Your health care provider can discuss the risks of the upper endoscopy procedure with you.
Culture - gastric tissue; Biopsy - gastric tissue
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Lee EL, Feldman M. Gastritis and gastropathies. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease Pathophysiology/Diagnosis/Management. 9th ed. Philadelphia, Pa: Elsevier Saunders; 2010:chap 51.
Updated by: Daniel Levy, MD, PhD, Infectious Diseases, Lutherville Personal Physicians, Lutherville, MD. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Bethanne Black, and the A.D.A.M. Editorial team.
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