Pediatric myocarditis is inflammation of the heart muscle in an infant or young child.
Myocarditis is rare in young children. It is slightly more common in older children and adults. It tends to be more severe in newborns and young infants than in children over age 2.
In children it is usually caused by viruses that reach the heart, such as the influenza (flu) virus, Coxsackie virus, parovirus, and adenovirus. However, it may also be caused by bacterial infections, including Lyme disease.
Other causes of pediatric myocarditis include:
The heart may be directly damaged by the virus or the bacteria that infect it. The body's own response to an infection can also damage the heart muscle (called the myocardium).
When you have an infection, your body's immune system produces special cells to fight off disease. If the infection affects your myocardium, the disease-fighting cells enter the heart.
While trying to get rid of the infection, the immune cells may also damage the heart muscle, causing it to become inflamed and swollen. This leads to symptoms of heart failure. In addition, the virus or bacteria may damage the heart muscle.
Symptoms may be mild at first and hard to detect. However, in newborns and infants, symptoms may sometimes appear suddenly. They may include symptoms of heart failure:
Symptoms in children over age 2 may also include:
Pediatric myocarditis can be hard to diagnose because the signs and symptoms often mimic those of other heart and lung diseases, or a bad case of the flu.
The doctor may hear a rapid heartbeat or abnormal heart sounds while listening to the child’s chest with a stethoscope. A physical examination may detect fluid in the lungs and swelling in the legs in older children.
There may be signs of infection, including fever and rashes.
A chest x-ray can show enlargement (swelling) of the heart. If the health care provider suspects myocarditis based on the exam and chest x-ray, an electrocardiogram may also be done to help make the diagnosis.
Further tests may include:
There is no cure for myocarditis. The heart muscle inflammation usually goes away on its own in time.
The goal of treatment is to support heart function until the inflammation goes away. Many children with this condition are admitted to a hospital. Because activity can strain the heart, it is often limited while the heart is inflamed.
Treatment may include:
How the child recovers from myocarditis depends on the cause and his or her overall health. With appropriate treatment, most children recover completely. However, some may have permanent heart disease.
Newborns have the highest risk for serious disease and complications (including death) due to myocarditis. In rare cases, damage to the heart muscle is so severe that a heart transplant is needed.
Make an appointment with your child's pediatrician if signs or symptoms of this condition occur.
There is no known prevention. However, prompt testing and treatment may reduce the disease risk.
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Behrman RE. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa: WB Saunders; 2007.
Park MK, Troxler RG. Pediatric Cardiology for Practitioners. 5th ed. St. Louis, Mo: Mosby, Inc; 2008.
Schwartz SM, Wessel DL. Medical cardiovascular support in acute viral myocarditis in children. Guidelines for the Treatment of Myocarditis in Infants and Children and Proceedings of the 2005 Pediatric Cardiac Intensive Care Symposium. Pediatr Crit Care Med. 7(6) Supplement:S12-S16, November 2006.
Updated by: Kurt R. Schumacher, MD, Pediatric Cardiology, University of Michigan Congenital Heart Center, Ann Arbor, MI. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc.
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