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Unified Medical Language System® (UMLS®)

New and Updated Sources (Expanded Representation Information) - 2014AB Release

General Information:

What's New for 2014AB

For 2014AB, there is 1 new source (LCH_NW) and 57 updated sources (including translation sources and 24 new subsources).

LCH_NW represents Northwestern University's subset of the Library of Congress Subject Heading concepts with mapping information to MeSH strings.

For detailed information about sources that are new or have had changes made (e.g. new term types, new attribute names, etc.):

Gene Ontology, GO2014_05_19
HUGO Gene Nomenclature Committee, HGNC2014_04
Library of Congress Subject Headings, Northwestern University subset, LCH_NW_2013
LOINC, LNC248
MEDCIN, MEDCIN3_2014_07_24
NCI Thesaurus, NCI2014_03E
RxNorm Vocabulary, RXNORM_14AA_140902F
SNOMED Clinical Terms, Spanish Language Edition, SCTSPA_2014_04_30
US Edition of SNOMED CT, ZNOMEDCT_US_2014_09_01
Veterinary Extension to SNOMED CT, SNOMEDCT_VET_2014_04_15

------------------------------------------

What's New to the Metathesaurus:

Attribute Name (ATN):
ANSWER_CODE
ANSWER_CODE_SYSTEM
EFFECTIVE_TIME
EXTERNALLY_DEFINED
EXTERNALLY_DEFINED_CODE_SYSTEM
GLOBAL_ID
GLOBAL_ID_CODE_SYSTEM
LOINC_SCORE
OID
PREMARKET_APPLICATION
SEQ_NO

Relationship Attribute(RELA)| RELA Inverse:
RO|active_moiety_of|has_active_moiety
RO|has_answer|answer_to
RO|has_inactive_ingredient|inactive_ingredient_of

Term Type (TTY):
LA
PSN

-------------------------------------------------------

Source: Gene Ontology VSAB: GO2014_05_19

Dropped relationship | relationship attribute (RELA):
RO|results_in

Discussion:

The relationship is no longer present in the source
data.

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Source: HUGO Gene Nomenclature Committee
VSAB: HGNC2014_04
Discussion:

New Specialist Database added: BioParadigms.

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Source: Library of Congress Subject Headings, Northwestern University subset
VSAB: LCH_NW_2013

1. New term type (TTY) | Suppressible value:
PT|N
XM|N

2. New relationship | relationship attribute (RELA) | RELA inverse:
RQ|mapped_from|mapped_to
RO| <blank>

3. New attribute name (ATN):
FROMRSAB
FROMVSAB
MAPSETRSAB
MAPSETVERSION
MAPSETVSAB
MTH_MAPFROMCOMPLEXITY
MTH_MAPFROMEXHAUSTIVE
MTH_MAPSETCOMPLEXITY
MTH_MAPTOCOMPLEXITY
MTH_MAPTOEXHAUSTIVE
SOS
TORSAB
TOVSAB
XMAP
XMAPFROM
XMAPTO

Discussion:

This is a new source which represents LCH concepts with linkings/mappings to MeSH strings (version: MSH2014_2014_02_10).

--------------------------------------------

Source: LOINC
VSAB: LNC248

1. New term type (TTY) | Suppressible value:
LA|N

2. New relationship | relationship attribute (RELA) | RELA inverse:
RO|has_answer|answer_to

3. New attribute name (ATN):
ANSWER_CODE
ANSWER_CODE_SYSTEM
EXTERNALLY_DEFINED
EXTERNALLY_DEFINED_CODE_SYSTEM
GLOBAL_ID
GLOBAL_ID_CODE_SYSTEM
LOINC_SCORE
OID
SEQ_NO

Discussion:
1. The new TTY, RELAs, and ATNs comes from the ANSWERS tab of the Accessory File called 'LOINC_248_SELECTED_FORMS.xlsx'. The file is published with each release and contains the answer information for specific LOINC concepts.
2. New TTY = LA represents the LOINC answer atom.
3. A 'has_answer'/'answer_to' relationship has been created between the concept and its answer.

-----------------------------------------------

Source: MEDCIN
VSAB: MEDCIN3_2014_07_24

New relationship | relationship attribute (RELA) | RELA inverse:
RO|has_scale_type|scale_type_of
RO|has_specimen_procedure|specimen_procedure_of
RO|has_specimen_source_identity|specimen_source_identity_of

------------------------------------------------

Source: NCI Thesaurus
VSAB: NCI2014_03E

This version includes:
NCI2014_BioC_1403E
NCI2014_BRIDG_1403E
NCI2014_CDC_1403E
NCI2014_CDISC_1403E
NCI2014_CRCH_1403E
NCI2014_CTCAE_1403E
NCI2014_CTEP-SDC_1403E
NCI2014_DCP_1403E
NCI2014_DICOM_1403E
NCI2014_DTP_1403E
NCI2014_FDA_1403E
NCI2014_ICH_1403E
NCI2014_JAX_1403E
NCI2014_KEGG_1403E
NCI2014_NCI-GLOSS_1403E
NCI2014_NCI-HL7_1403E
NCI2014_NCPDP_1403E
NCI2014_NICHD_1403E
NCI2014_PID_1403E
NCI2014_RENI_1403E
NCI2014_UCUM_1403E
NCI2014_ZFin_1403E

1. Dropped term type (TTY):
BRIDGPT
BioCPT
BioCSY
CDCPT
CDISCPT
CDISCSY
CRCHPT
CRCHSY
CTCAEPT
CTEP-SDCPT
CTEP-SDCSY
DCPPT
DCPSY
DICOMPT
DTPPT
DTPSY
FDAAB
FDAPT
FDASY
ICHAB
ICHPT
ICHSY
JAXPT
JAXSY
KEGGAB
KEGGPT
KEGGSY
NCI-GLOSSOP
NCI-GLOSSPT
NCI-GLOSSSY
NCI-HL7AB
NCI-HL7PT
NCI-HL7SY
NCPDPPT
NICHDAB
NICHDPT
NICHDSY
PIDPT
RENIDN
UCUMAB
UCUMPT
UCUMSY
ZFINPT
ZFINSY

2. Dropped attribute name (ATN):
CONTRIBUTING_SOURCE
ORIG_CODE
SUBSOURCE

Discussion:
1. The TTY format of subsource+TTY (e.g., UCUMPT) has been deprecated and replaced with individual subsources prepended by 'NCI2014_' (e.g., NCI2014_UCUM) which can be used with the standard TTYs (i.e., PT, SY).
2. With the creation of subsources, the ATN = ORIG_CODE has been deprecated. Subsource codes originally placed into the ATN = ORIG_CODE are now used in the code field.
3. With the creation of subsources, the ATN = CONTRIBUTING_SOURCE and ATN = SUBSOURCE are no longer needed.

----------------------------------------------

Source: RXNORM Vocabulary
VSAB: RXNORM_14AA_140902F

This version includes:
ATC_2014_14_09_02 (Anatomical Therapeutic Chemical Classification System)
GS_2014_08_01 (Gold Standard Drug Database)
MDDB_2014_07_30 (Master Drug Data Base. Medi-Span, a division of Wolters Kluwer Health)
MMSL_2014_08_01 (Multum MediSource Lexicon)
MMX_2014_08_04 (Micromedex RED BOOK)
MTHFDA_2011_06_01_13_05_06(FDA National Drug Code Directory)
MTHSPL_2014_08_25 (FDA Structured Product Labels)
NDDF_2014_08_06 (FDB MedKnowledge)
NDFRT_2014_09_02 (National Drug File)
NDFRT_FMTSME_2014_09_02 (National Drug File - FMTSME)
NDFRT_FDASPL_2014_09_02 (National Drug File - FDASPL)
VANDF_2014_07_17 (Veterans Health Administration National Drug File)

1. New term type (TTY) | Suppressible value | Source(s):
FN|N|NDRFT_2014_09_02
FN|O|NDRFT_2014_09_02
HT|N|NDRFT_2014_09_02
PSN|E|RXNORM_14AA_140902F
PSN|N|RXNORM_14AA_140902F
PSN|O|RXNORM_14AA_140902F

2. New relationship | relationship attribute (RELA) | RELA inverse:
RO|active_ingredient_of|has_active_ingredient
RO|active_metabolites_of|has_active_metabolites
RO|active_moiety_of|has_active_moiety
RO|chemical_structure_of|has_chemical_structure
RO|contraindicated_with_disease|disease_with_contraindication
RO|contraindicating_class_of|has_contraindicating_class
RO|contraindicating_mechanism_of_action_of|has_contraindicating_mechanism_of_action
RO|contraindicating_physiologic_effect_of|has_contraindicating_physiologic_effect
RO|effect_may_be_inhibited_by|may_inhibit_effect_of
RO|has_active_ingredient|active_ingredient_of
RO|has_active_metabolites|active_metabolites_of
RO|has_active_moiety|active_moiety_of
RO|has_chemical_structure|chemical_structure_of
RO|has_contraindicated_drug|drug_contraindicated_for
RO|has_contraindicating_class|contraindicating_class_of
RO|has_contraindicating_mechanism_of_action|contraindicating_mechanism_of_action_of RO|has_contraindicating_physiologic_effect|contraindicating_physiologic_effect_of
RO|has_inactive_ingredient|inactive_ingredient_of
RO|has_mechanism_of_action|mechanism_of_action_of
RO|has_pharmacokinetics|pharmacokinetics_of
RO|has_physiologic_effect|physiologic_effect_of
RO|has_product_component|product_component_of
RO|has_therapeutic_class|therapeutic_class_of
RO|inactive_ingredient_of|has_inactive_ingredient
RO|induced_by|induces
RO|induces|induced_by
RO|may_be_diagnosed_by|may_diagnose
RO|may_be_prevented_by|may_prevent
RO|may_be_treated_by|may_treat
RO|may_diagnose|may_be_diagnosed_by
RO|may_inhibit_effect_of|effect_may_be_inhibited_by
RO|may_prevent|may_be_prevented_by
RO|may_treat|may_be_treated_by
RO|mechanism_of_action_of|has_mechanism_of_action
RO|metabolic_site_of|site_of_metabolism
RO|pharmacokinetics_of|has_pharmacokinetics
RO|physiologic_effect_of|has_physiologic_effect
RO|product_component_of|has_product_component
RO|site_of_metabolism|metabolic_site_of
RO|therapeutic_class_of|has_therapeutic_class

3. New attribute name (ATN) | Source(s):
FDA_UNII_CODE|NDFRT_2014_09_02
LEVEL|NDFRT_2014_09_02
MESH_DEFINITION|NDFRT_2014_09_02
MESH_DUI|NDFRT_2014_09_02
MESH_NAME|NDFRT_2014_09_02
MESH_UI|NDFRT_2014_09_02
NDFRT_KIND|NDFRT_2014_09_02
NDF_UNITS|NDFRT_2014_09_02
NUI|NDFRT_2014_09_02
PREMARKET_APPLICATION|MTHSPL_2014_08_25
SNOMED_CID|NDFRT_2014_09_02
STRENGTH|NDFRT_2014_09_02
VANDF_RECORD|NDFRT_2014_09_02
VA_IEN|NDFRT_2014_09_02
VUID|NDFRT_2014_09_02

4. Dropped attribute name (ATN):
FDASRS
UNII_CODE

Discussion:
1. Two new subsources = NDFRT_FDASPL and NDFRT_FMTSME. These sources provide relationship data only and no atoms.
2. TTY = PSN (Prescribable name) and TTY = FN (Full form of descriptor).
3. MTHFDA is included in each Metathesaurus release as part of RxNorm, however, it was not updated in this version. MTHFDA was last updated in 2011.
4. Selected portions of MSH and SNOMEDCT_US are included in the RxNorm release files, however, they are not processed as part of RxNorm for the Metathesaurus except in assigning RXCUI and RXAUI attributes.

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Source: SNOMED Clinical Terms, Spanish Language Edition
VSAB: SCTSPA_2014_04_30
New term type (TTY) | Suppressible value:
MTH_OP|O

Discussion:
TTY = MTH_OP represents a Metathesaurus-created obsolete preferred term.

---------------------------------------------------------------------

Source: US Edition of SNOMED CT
VSAB: SNOMEDCT_US_2014_09_01

1. Dropped relationship | relationship attribute (RELA):
RO|translation_of
2. New attribute name (ATN):
EFFECTIVE_TIME

Discussion:
1. ATN = EFFECTIVE_TIME is being created for concepts only.
2. A new set of SNOMEDCT_US to ICD10CM mappings is included in this release.

-----------------------------------------------

Source: Veterinary Extension to SNOMED CT
VSAB: SNOMEDCT_VET_2014_04_15

New relationship | relationship attribute(RELA) | RELA inverse:
RN|part_of|has_part
RO|has_active_ingredient|active_ingredient_of
RO|has_direct_morphology|direct_morphology_of

Discussion:
SNOMEDCT_VET asserts some relationships between concepts from the SNOMEDCT core.