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Unified Medical Language System® (UMLS®)

RxNorm Release Notes

August Release - 08/05/2013

This release of RxNorm is consistent with the 2013AA UMLS Metathesaurus release. For additional information about RxNorm releases, including scripts for loading the RxNorm data into Oracle and MySQL databases, read the RxNorm technical documentation.

Sources

The following sources have been updated since the previous RxNorm release:

Source NameSABDate Updated
Anatomical Therapeutic Chemical Classification System ATC 2013
Gold Standard Drug Database GS 07/03/2013
Medi-Span Master Drug Data Base MDDB 07/03/2013
Multum MediSource Lexicon MMSL 07/01/2013
Micromedex RED BOOK MMX 07/01/2013
FDA Structured Product Labels MTHSPL 07/29/2013
FDB MedKnowledge (formerly NDDF Plus) NDDF 07/10/2013
Veterans Health Administration National Drug File VANDF 06/24/2013

 

The following sources have not been updated in this release:

Source NameSABDate Updated
Medical Subject Headings (MeSH) MSH 01/21/2013
FDA National Drug Code Directory MTHFDA 06/01/2011
Veterans Health Administration National Drug File - Reference Terminology NDFRT 07/01/2013
SNOMED Clinical Terms (drug information) SNOMEDCT 01/31/2013

Data Changes

This release of RxNorm includes a new source - Anatomical Therapeutic Chemical Classification System (ATC). The World Health Organization (WHO) Collaborating Centre for Drug Statistics Methodology maintains ATC. ATC classifies chemical substances into 14 anatomical groups, which are divided into three levels of pharmacological, chemical, and therapeutic subgroups. Members of these groups and subgroups include approximately 4,500 ingredients.

To represent ATC in RxNorm, we use the ‘PT’ term type (TTY) for group and subgroup names and the ‘IN’ TTY for ingredient names. We also created ‘RXN_PT’ and ‘RXN_IN’ TTYs to disambiguate some group, subgroup, and ingredient names. For example, there is a ‘PT’ for the subgroup ‘Antibiotics’ within the subgroup ‘Drugs for treatment of tuberculosis’. We also created a string, ‘Antibiotics, Antitubercular’, with a TTY of ‘RXN_PT’ to clarify the context of this subgroup. We relate ingredients to their respective subgroups using ‘member_of’/’has_member’ relationships, and groups and subgroups relate to each other with ‘isa’/’inverse_isa’ relationships.

For more information about ATC, visit the WHO ATC page.

Data Counts

Term Type or AttributeNumber
Active GPCK forms 335
Active BPCK forms 408
Active SCD forms 20,052
Active SBD forms 11,006
Active RXNORM MIN atoms 3,844
Active RXNORM IN atoms 9,147
Active RXNORM PIN atoms 2,177
Active RXNORM BN atoms 6,940
Active RXNORM DF atoms 104
   
Obsolete GPCK forms 118
Obsolete BPCK forms 96
Obsolete SCD forms 13,785
Obsolete SBD forms 9,585
Obsolete RXNORM MIN atoms 0
Obsolete RXNORM IN atoms 0
Obsolete RXNORM PIN atoms 0
Obsolete RXNORM BN atoms 8,758
Obsolete RXNORM DF atoms 51
Editor-suppressed SCD forms 1,093
Editor-suppressed SBD forms 902
OCD atoms 311,395
   
Source-asserted NDC codes 1,245,556
Distinct Source-asserted NDC codes 558,772
SAB=RXNORM NDC codes 192,460
Distinct SAB=RXNORM NDC codes 192,460