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Squaring the Circle: Validation Without Ground Truth
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Peter Ratiu, Ron Kikinis
Surgical Planning Laboratory, Department of Radiology
Brigham and Women's Hospital, Harvard Medical School
ratiu@bwh.harvard.edu
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Abstract
Insight is a software toolkit
being developed by a consortium of academic and industrial research institutions
sponsored by the National Library of Medicine and its partner institutes
and agencies. An essential component of this toolkit is the development
of a validation methodology for various segmentation techniques. In this
paper we present the outlines of the principles for establishing a quantitative
assessment of the accuracy of segmentation techniques based on mutual information
of anatomical knowledge and we discuss the the advantages and limitations
of the validation suite outlined.
Keywords: anatomy, computational anatomy, segmentation, validation.
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