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Medical Technology

Since 1776, the history of medical technology in the United States has often reflected the broader scientific, industrial, and social progress of the nation. From the earliest surgical tools used during the Revolutionary War to more recent developments such as artificial heart valves and magnetic resonance imaging (MRI), U.S. technical innovation has always proceeded hand in hand with improvements in patient health. Learn more about some of these incredible inventions in this digital gallery.

1776-1826
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1776-1826

In the Early Republic, varying levels of medical training and limited professional standards yielded loosely organized practice of medicine. People sought out common therapeutic practices—including bloodletting, purging, surgery, and home remedies—from family members, communities, and physicians. Shaped by wars and limited public sanitation, smallpox, yellow fever, and other infectious diseases were major health concerns. The spread of smallpox inoculation, expanding medical education, and scientific inquiry advanced the medical profession. Explore a selection of NLM items produced between 1776 and 1826. Topics include wartime medicine, smallpox inoculation, Native American health and healing, yellow fever epidemics, botanicals and herbal remedies, and more.

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1827-1876
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1827-1876

American medicine became more organized during the 19th century as medical schools, hospitals, and professional societies expanded, though standards and training varied widely. Physicians practiced surgery, obstetrics, and emerging scientific medicine, while many people also turned to homeopathy and other alternative therapies. Infectious diseases such as cholera, smallpox, and rabies remained major threats, prompting growing interest in quarantine, sanitation, and public health. Significant advances included the use of ether anesthesia, improvements from Civil War medicine, and the development of professional nursing. Presented is an assortment of National Library of Medicine collection items printed between 1827 and 1876, covering topics such as homeopathy, nursing, infectious disease, administering ether, sanitation, women in medicine, Civil War medicine, and more.

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1877-1926
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1877-1926

Between 1877 and 1926, American medicine became increasingly scientific and professionalized as medical education and licensing became required by the states. Physicians relied on laboratory science, surgery, nursing care, and new diagnostic tools, while some Americans used widely advertised patent medicines alongside conventional treatments. Infectious diseases such as tuberculosis, influenza, rabies, and yellow fever remained major concerns, driving advances in public health and disease prevention, including the development of several vaccines. Germ theory, antiseptic surgery, X-rays, bacteriology, and the discovery of insulin transformed medical practice and outcomes. View this selection of items from the NLM collection produced from 1877 to 1926, which include works about pharmacology, surgery, infectious disease, public health, nursing, World War I medicine, and more.

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1927-1976
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1927-1976

By the mid-20th century, American medicine had become highly professionalized as physicians, nurses, hospitals, and public health agencies took on leading roles in healthcare. Medical practice increasingly relied on laboratory science, pharmaceuticals, vaccinations, and advanced technologies. These changes led to many Americans receiving care through hospitals, clinics, and expanding insurance systems. Infectious diseases declined as sulfa drugs, antibiotics, and vaccines transformed treatment and prevention. Chronic diseases, smoking-related illnesses, and environmental health concerns gained attention. Major medical breakthroughs included blood banking, open-heart surgery, organ transplantation, and DNA research. Explore a selection of NLM collection items produced between 1927 and 1976 about the discovery of DNA, substance use, World War II medicine, environmental health, computers in medicine, biotechnology, and more.

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1977-2026
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1977-2026

Since 1977, American medicine has become more technologically advanced and evidence based. Physicians, nurses, and allied professionals deliver specialized and team-based care. Patients access health services through hospitals, outpatient clinics, telemedicine, and digital health platforms, reflecting major changes in communications and access. Many health concerns from years past persist, like cancer and mental health disorders, while new ones have emerged, including the opioid epidemic, infectious diseases such as Ebola and COVID-19, and chronic conditions tied to lifestyle and aging populations. Advances in genomics, imaging, immunotherapy, and artificial intelligence continue to transform diagnosis and treatment, alongside major public health campaigns and public policy responses. Browse these NLM collection items created between 1977 and 2026, on subjects including HIV/AIDS, COVID-19, the opioid epidemic, mental health, telemedicine, public health communications, and more.

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Anatomy and Surgery
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Anatomy and Surgery

In the United States, the histories of anatomy and surgery have long been closely intertwined. Whereas early physicians often relied on limited anatomical knowledge and rudimentary surgical procedures to treat patients, later improvements in fields such as education, anesthesia, antibiotics, and blood transfusion made operations safer and more effective. Learn more about some of these important historical developments in this digital gallery.

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Cultures of Medicine
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Cultures of Medicine

Medicine has always involved cultural forces that impact the discipline as a whole. These forces impact the way in which individual physicians undertake their work and researchers discover various treatments for diseases. From stories about doctors and patients to the organizations that support their efforts, medical professionals are part of a broader system that helps to keep the entire nation healthy. Scroll through this digital gallery to learn more about the cultural history of medicine in the U.S.

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Diseases and Conditions
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Diseases and Conditions

Over the past 250 years, the list of diseases and conditions that affect people in the U.S. has changed dramatically. In the early Republic, cholera, yellow fever, and smallpox were among the leading causes of death. Today, advances in sanitation and public health mean that these illnesses have been eradicated or replaced, leaving chronic conditions such as cancer, diabetes, and heart disease as the most pressing health concerns. Learn about the changing history of diseases and related conditions in this digital gallery.

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Drugs and Treatments
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Drugs and Treatments

Drugs and therapeutic treatments have played an important role in U.S. medicine since the founding of the country in 1776. Whereas early physicians generally relied on traditional methods such as bloodletting and herbal remedies, later advances in vaccines, pharmaceuticals, antibiotics, and chemotherapy have helped to radically to improve patients’ health. Learn more about the development of some of these innovative drugs and treatments in this digital gallery.

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Laboratory Science
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Laboratory Science

Researchers working in laboratories across the United States have made some of the most important medical breakthroughs of the last 250 years. These include the first use of general anesthesia and the discovery of the cause of yellow fever, as well as more recent innovations like recombinant DNA technology, GLP-1 inhibitors, and CAR-T Cell therapy. Learn about a handful of these important laboratory discoveries in this digital gallery.

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Medical Technology
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Medical Technology

Since 1776, the history of medical technology in the United States has often reflected the broader scientific, industrial, and social progress of the nation. From the earliest surgical tools used during the Revolutionary War to more recent developments such as artificial heart valves and magnetic resonance imaging (MRI), U.S. technical innovation has always proceeded hand in hand with improvements in patient health. Learn more about some of these incredible inventions in this digital gallery.

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Military Medicine
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Military Medicine

Throughout its history, the United States has participated in numerous armed conflicts that have contributed to the growth of military medicine. From the War of Independence to the U.S. Civil War and more recent struggles in Europe, Vietnam, and Afghanistan, the country has relied on a dedicated group of doctors, nurses, and field medics to keep their troops healthy and combat ready. Learn more about their stories and the history of U.S. military medicine in this digital gallery.

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Mind and Brain
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Mind and Brain

Between the founding of the U.S. in 1776 and today, medical research into patients’ minds and brains has shifted from the field of philosophy to the natural and social sciences. During this time, researchers have become increasingly interested in the ways in which various physical and chemical structures in the brain contribute to human cognition. This in turn has revolutionized how we see learning, memory, and indeed mental health. Learn more about this historical transition in the digital gallery below.

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Preventive Medicine
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Preventive Medicine

Though we often think of preventive medicine as a recent historical development, the idea of taking proactive steps to ensure personal health is at least as old as the United States itself. For centuries, U.S. doctors and physicians have recommended a wide variety of herbal remedies, workout regimes, and dietary plans—each designed to help their patients live a healthier lifestyle. Learn about some of these innovative and unusual therapies in this digital gallery.

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Public Health
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Public Health

Public health has shaped the medical, political, and social life of the United States since the nation was first born two and a half centuries ago. Beginning with the efforts of local officials to contain an outbreak of Yellow Fever in Philadelphia in 1793, the U.S. government has consistently played an important role in improving living conditions and promoting healthy behaviors in communities all across the country. Learn more about the history of U.S. public health in this digital gallery.

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Audiovisuals
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Audiovisuals

Moving images serve as a vital tool for health education, document significant events and breakthroughs in medicine, and provide a way of sharing scientific scholarship. Explore this selection of audiovisual materials in the NLM collection, produced over the past century, originally in film, videocassette, and webcast.

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Born-Digital
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Born-Digital

Since the mid-20th century, digital media has transformed American health and medicine, changing how medical knowledge is created, shared, and preserved; empowering patients with greater access to information; enabling community action in the pursuit of wellbeing; and accelerating biomedical research and discovery. Learn about born-digital materials in the NLM collection, including websites and software, in this digital gallery.

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Manuscripts
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Manuscripts

Medical manuscripts document the development of American medicine. Physicians, researchers, students, hospitals, and public health officials manually record and collect observations, treatments, research findings, and institutional activities. These records support medical education and facilitate the exchange of knowledge. Today, medical manuscripts remain invaluable sources for understanding the scientific, social, and cultural history of health and medicine in the United States. Explore this selection of working notes and correspondence from clinicians, researchers, and patients.

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Still Images
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Still Images

From anatomical drawings and clinical photographs to public health posters and advertisements, still images help doctors diagnose illness, communicate scientific knowledge, educate the public, and shape perceptions of medicine. They have also served as records of medical practice, scientific discovery, and patient experience, preserving visual evidence of how health and medicine have evolved over time. Explore a selection of these still images from the collection in this digital gallery.

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Texts
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Texts

Over the past 250 years, medical texts have been the primary means of organizing and sharing medical knowledge gained in America. Textbooks, journals, and reference works have standardized medical education and clinical practice while supporting the professionalization of the field. They have enabled scientific communication, recorded shifting understandings of disease, and translated research into practice. Medical texts also provide a lasting scholarly record that continues to inform education, care, and historical research. Explore this assortment of medical texts from the NLM collection.

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27 Images

An illustration from an old book depicting six different surgical implements, including a saw, a hook, and a clamp.

A System of Surgery, Benjamin Bell, Worcester, MA: Isaiah Thomas, 1791

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An illustration from an old book depicting six different surgical implements, including a saw, a hook, and a clamp.
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The title page of Evidences of the Efficacy of Doctor Perkinss Patent Metallic Instruments.

Evidences of the Efficacy of Doctor Perkins's Patent Metallic Instruments, Elisha Perkins, New London, CT: Samuel Green, 1797

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The title page of Evidences of the Efficacy of Doctor Perkinss Patent Metallic Instruments.
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An illustration of a man strapped to a chair with a large wooden block covering the top part of his head and eyes.

"The Tranquilizing Chair of Benjamin Rush" from The Philadelphia Medical Museum, Benjamin Rush, Philadelphia, PA: John Coxe Redman, 1811

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An illustration of a man strapped to a chair with a large wooden block covering the top part of his head and eyes.
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An illustration of a man with various gash wounds on his head and face.

Elements of Surgery, John Syng Dorsey, Philadelphia, PA: Edward & Richard Parker, 1813

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An illustration of a man with various gash wounds on his head and face.
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An illustration of a boy wearing a headband that is attached by a chain to medical harness on his chest, along with further images of surgical implements such as scissors and a scalpel.

The First Lines of the Practice of Surgery, Samuel Cooper, New York, NY: James V. Seaman, 1822

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An illustration of a boy wearing a headband that is attached by a chain to medical harness on his chest, along with further images of surgical implements such as scissors and a scalpel.
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An illustration of two children using various orthopedic devices to straighten their spines.

Spinal Diseases, Both Structural and Functional, Usher Parsons, Louisville, KY: Kling and Teschemacher, 1843

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An illustration of two children using various orthopedic devices to straighten their spines.
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Seven small illustrations accompanying the text of an article by Dr. Hitchcock on the manufacture of dentures.

"The Dental Art" from Gleason's Pictorial Drawing-Room Companion, Thomas B. Hitchcock, Boston, MA: Frederick Gleason, 1853

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Seven small illustrations accompanying the text of an article by Dr. Hitchcock on the manufacture of dentures.
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An illustration of several men standing in a row, each of whom has an artificial leg.

Artificial Limbs: Advertisement for Palmer and Co. (Wood Engraving), New York, NY, 1857

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An illustration of several men standing in a row, each of whom has an artificial leg.
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  • Exhibition - Life and Limb: The Toll of the American Civil War
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A photograph of an open wagon with padded benches, wooden wheels and a canvas roof that rolls down the sides. Writing on the side reads Built at U.S. Repair Shopts Lincoln Depot Washington D.C. Scale 5 in. to 1 ft.

"A Model of a Rucker Horse Drawn Ambulance" (Photoprint), 1866

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A photograph of an open wagon with padded benches, wooden wheels and a canvas roof that rolls down the sides. Writing on the side reads Built at U.S. Repair Shopts Lincoln Depot Washington D.C. Scale 5 in. to 1 ft.
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A page from a book with two labeled illustrations of surgical instruments involving a chain loop which can be tightened.

Clinical Notes on Uterine Surgery, James Marion Sims, New York, NY: Wood, 1867

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A page from a book with two labeled illustrations of surgical instruments involving a chain loop which can be tightened.
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A black and white book page showing illustrations of a side view, a top view, and a cross-sectional view of an all glass model toilet.

"Three Views of an All Model Glass Toilet" from The Hartford Sanitary Plumbing Co.'s Patent Glass Water-Closet, Hartford Sanitary Plumbing Co., Hartford, CT, 1881

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A black and white book page showing illustrations of a side view, a top view, and a cross-sectional view of an all glass model toilet.
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A book page with two color illustrations of microscope images showing different aspects of tuberculosis infection on the human tongue.

An American Text-Book of Surgery, Charles Burnett, Philadelphia, PA: W. B. Saunders, 1892

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A book page with two color illustrations of microscope images showing different aspects of tuberculosis infection on the human tongue.
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An x-ray photograph showing the foot of a man wearing a boot

X-ray Photographs from The X-Ray: Or, Photography of the Invisible, William James Morton, New York, NY: American Technical Book Co., 1896

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An x-ray photograph showing the foot of a man wearing a boot
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A photograph of a handheld apparatus with which one can view a photograph closely; there is an eyepiece and photo stand connected by a cherry wood handle; the photographbeing viewed is of a womans lower face with a large cold sore on the lower lip.

The Stereoscopic Skin Clinic, National Library of Medicine, New York, NY: Blast Books, 1910

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A photograph of a handheld apparatus with which one can view a photograph closely; there is an eyepiece and photo stand connected by a cherry wood handle; the photographbeing viewed is of a womans lower face with a large cold sore on the lower lip.
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A movie still of a white boy with dirty teeth, smiling into the camera.

Ask Your Dentist, 1928

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A movie still of a white boy with dirty teeth, smiling into the camera.
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  • Medicine on Screen: Films and Essays from NLM
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In a black and white photograph, a group of people consisting of one black man, five white, female nurses, two white, male truck drivers, and two white men, stand in front of two trucks.

Charles Drew with the First Mobile Blood Collecting Unit, 1941 (Photoprint), Charles Drew, 1941

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In a black and white photograph, a group of people consisting of one black man, five white, female nurses, two white, male truck drivers, and two white men, stand in front of two trucks.
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  • Profiles in Science - The Charles R. Drew Papers
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Black and white still image of wounded man strapped in a special helicopter stretcher.

Final Preparations Made for Evacuation of a Wounded Man to the 1st Mobile Army Surgical Hospital, Chechon, Korea (Photoprint), Army Signal Corps Photographs, Chechon, Korea: U.S. Army, 1951

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Black and white still image of wounded man strapped in a special helicopter stretcher.
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  • Profiles in Science - The Michael E. DeBakey Papers
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Black and white film of cultured cells taken originally from a patient with cervical carcinoma.

The Hela Cell Strain: Cervical Carcinoma, Pomerat, Charles M., Washington, DC: Association of American Medical Colleges, 1956

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Black and white film of cultured cells taken originally from a patient with cervical carcinoma.
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A black and white photograph of an astronaut standing on the surface of the moon in a spacesuit, the reflection of the glass window on his helmet showing another astronaut taking the picture.

The Centers for Disease Control and Prevention Provided Quarantine Equipment and Procedures for the United States Space Program, Including the Apollo Moon Landings (Photoprint), Centers for Disease Control and Prevention (CDC), Atlanta, GA, 1969

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A black and white photograph of an astronaut standing on the surface of the moon in a spacesuit, the reflection of the glass window on his helmet showing another astronaut taking the picture.
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A black and white photograph of Joshua Lederberg at an old computer.

Joshua Lederberg at a LINC Computer Teletype (Photoprint), Stanford University School of Medicine, 1974

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A black and white photograph of Joshua Lederberg at an old computer.
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  • Profiles in Science - The Joshua Lederberg Papers
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In a black and white photograph, a white woman and three white men talk around a coffeetable covered in papers that one of the white men is writing on; a chalkboard with writing appears in the background.

Maxine Singer, Norton Zinder, Sydney Brenner, and Paul Berg at the 1975 Asilomar Conference on Recombinant DNA (Photoprint), 1975

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In a black and white photograph, a white woman and three white men talk around a coffeetable covered in papers that one of the white men is writing on; a chalkboard with writing appears in the background.
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The first page of a journal article

Heart Transplantation: No Longer an Experiment, Michael DeBakey, Houston, TX: Texas Medical Association, 1988

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The first page of a journal article
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Start screen for version 4.0 of an early computer tutorial with graphics of the NLM building and an american flag.

"HowTo" for GRATEFUL MED Version 4.0 Software, Lister Hill National Center for Biomedical Communications, Bethesda, MD: National Library of Medicine (NLM), 1989

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Start screen for version 4.0 of an early computer tutorial with graphics of the NLM building and an american flag.
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Title screen of a public service announcement video including an image of a red haired child getting an ear exam and the tagline: Contact you Public Library for more information.

Medical Questions: MEDLINE Has Answers, National Library of Medicine (NLM), Bethesda, MD, 1996

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Title screen of a public service announcement video including an image of a red haired child getting an ear exam and the tagline: Contact you Public Library for more information.
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An art print of a chaotic hospital scene shows healthcare workers treating patients with infectious diseases amid death, fear, and heavy precautions, highlighting the severity and spread of illness.

Emerging Infectious Diseases (Linoleum Block Over Lithograph), Eric Avery, Galveston, TX, 2000

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An art print of a chaotic hospital scene shows healthcare workers treating patients with infectious diseases amid death, fear, and heavy precautions, highlighting the severity and spread of illness.
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First page of a report featuring title and abstract and headings: A Look at the Numbers and Dose-Omission Errors in the Labot and Delivery Unit.

How Smartphones Are Changing Health Care For Consumers and Providers, Jane Sarasohn-Kahn, Oakland, CA: California HealthCare Foundation, 2010

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First page of a report featuring title and abstract and headings: A Look at the Numbers and Dose-Omission Errors in the Labot and Delivery Unit.
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Document cover page illustrated with a laptop showing a docotor on the screen during a telehealth appointment.

Effective Strategies for Sustaining and Optimizing Telehealth in Primary Care, Danielle Carder and Courtney Furrow-White, Irvine, TX: Association of American Medical Colleges and Vizient, 2023

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Document cover page illustrated with a laptop showing a docotor on the screen during a telehealth appointment.
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