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Osmotic diuresis

Osmotic diuresis is increased urination due to the presence of certain substances in the fluid filtered by the kidneys. This fluid eventually becomes urine. These substances cause additional water to come into the urine, increasing its amount.


Osmotic diuresis can be caused by:

  • High blood sugar (glucose)
  • Use of certain medications, such as Mannitol


Kamel KS, Davids MR, Lin S-H, Halperin ML. Interpretation of electrolyte and acid-base parameters in blood and urine. In: Taal MW, Chertow GM, Marsden PA, et al., eds.Brenner & Rector's The Kidney.

Landry DW, Bazari H. Approach to the patient with renal disease. In: Goldman L, Schafer AI, eds.Goldman's Cecil Medicine.

Update Date 8/17/2014

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