OverviewBiguanides (Metformin) tell the liver to decrease its production of glucose, which lowers glucose levels in the bloodstream.
Update Date 8/5/2014
Updated by: Brent Wisse, MD, Associate Professor of Medicine, Division of Metabolism, Endocrinology & Nutrition, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.