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 May 23, 2005 [posted]
 Clinical Prediction Guides Added to PubMed® Clinical Queries

drop cap letter for a new clinical study category called Clinical Prediction Guides has been added to the PubMed Clinical Queries page. (See Figure 1.)

  figure 1: graphic

Clinical Prediction Guides pertain to the prediction of some aspect of a disease or condition and have been advocated as a mechanism for enhancing clinical judgement. Clinical prediction studies develop or validate rules, guides, indexes, equations, scales, scores or models to predict a diagnosis, prognosis, risk (etiology), therapeutic response, therapeutic drug level or clinical outcome. An example of a clinical prediction guide is the Ottawa ankle rule. Can Fam Physician. 1996 Mar;42:478-80.

Ottawa ankle rules.

Stiell I.

Medical Research Council of Canada Research Personnel Program, Ottawa.

The Ottawa ankle rule project demonstrated that more than 95% of patients with ankle injuries had radiographic examinations but that 85% of the films showed no fractures. A group of Ottawa emergency physicians developed two rules to identify clinically important fractures of the malleoli and the midfoot. Use of these rules reduced radiographic examinations by 28% for the ankle and 14% for the foot.

Publication Types:
  • Clinical Trial
  • Controlled Clinical Trial

PMID: 8616287 [PubMed - indexed for MEDLINE]

The search strategies (broad and narrow scope) for this category have been developed by Wong SS, et al., as described in the following publication:

Developing optimal search strategies for detecting sound clinical prediction studies in MEDLINE. AMIA Annu Symp Proc. 2003;:728-32. PMID: 14728269

By Ione Auston
National Information Center on Health Services Research and Health Care Technology (NICHSR)

black line separting article from citation

Auston I. Clinical Prediction Guides Added to PubMed® Clinical Queries. NLM Tech Bull. 2005 May-Jun;(344):e7.


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