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Unified Medical Language System® (UMLS®)

MEDLINE Current Files Source Information

The MEDLINE® Current Files were developed and are maintained by the U.S. National Library of Medicine (NLM).

The MEDLINE database, produced by NLM, includes over 18 million journal article references related to the life sciences, with a focus on biomedicine.

MEDLINE Backfiles provide co-occurrence data for Medical Subject Headings (MeSH®) assigned to MEDLINE citations.

MEDLINE Current Files contain MEDLINE co-occurrence data for MeSH for the past five years. For example, the MEDLINE Current Files for the 2010AA UMLS release included co-occurrence data for 2005-2010.

MEDLINE Current Files data is located in the MRCOC.RRF file in the Metathesaurus. There are no concepts included in this source.

For more information about MeSH in the Metathesaurus, see the MeSH source synopsis.

Metathesaurus Update Frequency
MEDLINE Current Files are updated annually.

Sites Consulted

  1. Fact sheet: MEDLINE® [Internet]. Bethesda (MD): National Library of Medicine (US); 2004 Nov 17 [updated 2010 Jun 2; cited 2010 Jul 30]. [about 6 screens]. Available from:
  2. UMLS® Reference Manual [Internet]. Bethesda (MD): National Library of Medicine (US); 2009 Sep. Chapter 3.3.10, Co-occurring Concepts (File = MRCOC.RRF); [cited 2010 Jul 30]; [8 paragraphs]. Available from: