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Unified Medical Language System® (UMLS®)

KEGG Pathway Database Source Information

KEGG (Kyoto Encyclopedia of Genes and Genomes) is produced by Kanehisa Laboratories, Kyoto, Japan, in collaboration with Bioinformatics Center, Institute for Chemical Research, Kyoto University and Human Genome Center, Institute of Medical Science, University of Tokyo.

KEGG is used to link a KEGG pathway reference to the primary pathway information. It enables the understanding of high-level functions and utilities of the biological system, such as the cell, the organism and the ecosystem, from molecular-level information.

KEGG ID codes are used for pathway maps, representing molecular pathways for metabolism, genetic information processing, environmental information processing, other cellular processes, human diseases, and drug development.

KEGG is widely used as a reference knowledge base for integration and interpretation of large-scale datasets generated by genome sequencing and other high-throughput experimental technologies. It is intended to meet the needs of translational bioinformatics, in terms of both translating research results into practical applications and translating scientific knowledge into layman's terms.

Metathesaurus Update Frequency
KEGG is updated annually as part of the NCI Thesaurus in the Metathesaurus.

Sites Consulted

  1. KEGG Primer: An Introduction to Pathway Analysis Using KEGG [Internet]. [Bethesda (MD): Aoki-Kinoshita, K.F. et al.; c2007 [cited 2014 Dec 04]. Available from:
  2. KEGG: Kyoto Encyclopedia of Genes and Genomes [Internet]. [Kyoto?]: Kanehisa Laboratories, c1995-2014 [cited 2014 Dec 04]. Available from: