MedlinePlus Drug Information: Quinine

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Other drug names:	A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9

Quinine

(kwye' nine)

Contents of this page:
Why is this medication prescribed? How should this medicine be used? Other uses for this medicine What special precautions should I follow? What should I do if I forget a dose?	What side effects can this medication cause? What storage conditions are needed for this medicine? In case of emergency/overdose What other information should I know? Brand names

IMPORTANT WARNING: Return to top

[Posted 12/12/2006] FDA informed healthcare professionals and consumers that the Agency ordered firms to stop marketing unapproved drug products containing quinine, citing serious safety concerns, including deaths associated with quinine products. There are multiple unapproved products containing quinine currently on the market, used off-label to treat leg cramps and similar conditions. Since 1969, FDA received 665 reports of adverse events with serious outcomes associated with quinine use, including 93 deaths. Quinine drugs are associated with serious side effects, such as cardiac arrhythmias, thrombocytopenia, and severe hypersensitivity reactions. Qualaquin, manufactured by Mutual Pharmaceutical Company, is the only quinine product approved by the FDA. For more information visit the FDA website at: http://www.fda.gov/medwatch/safety/2006/safety06.htm#Quinine and http://www.fda.gov/bbs/topics/NEWS/2006/NEW01521.html.

If you are taking quinine and have any questions about your medication after reading this information, you should contact your doctor or pharmacist. Do not change your dose, how often you take your medication, or the length of time you are to take it without first talking to your healthcare provider.

Why is this medication prescribed? Return to top

See the MedWatch notification at the beginning of the monograph.

Quinine is used to prevent and treat malaria.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How should this medicine be used? Return to top

Quinine comes in capsules and tablets to take by mouth. It usually is taken three times a day (every 8 hours) for 3 days for malaria attacks, twice a day for 6 weeks to prevent or suppress malaria, and at bedtime for leg cramps. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take quinine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Since quinine is very bitter, do not chew tablets before swallowing them.

Other uses for this medicine Return to top

Quinine is also used to treat nighttime leg muscle cramps. Talk to your doctor about the possible risks of using this drug for your condition.

What special precautions should I follow? Return to top

See the MedWatch notification at the beginning of the monograph.

Before taking quinine,

tell your doctor and pharmacist if you are allergic to quinine, quinidine, or any other drugs.
tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially acetazolamide, antacids, anticoagulants ('blood thinners') such as warfarin (Coumadin), cimetidine (Tagamet), digitoxin, digoxin (Lanoxin), quinidine, and vitamins. Do not take antacids that contain aluminum (e.g., aluminum hydroxide) or sodium bicarbonate without talking to your doctor. Also, avoid tonic water and nonprescription cold preparations that contain quinine.
tell your doctor if you have or have ever had G-6-PD deficiency (an inherited blood disease), ringing ears, eye problems, or blackwater fever.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking quinine, call your doctor immediately.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking quinine.

What should I do if I forget a dose? Return to top

Take the missed dose as soon as you remember it, and take any remaining doses for that day at evenly spaced intervals. However, if you take only one dose per day at bedtime, skip the missed dose completely. Do not take a double dose to make up for a missed one.

What side effects can this medication cause? Return to top

See the MedWatch notification at the beginning of the monograph.

Quinine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

stomach pain
vomiting
stomach upset
dizziness
headache
sweating
restlessness
confusion
apprehension

If you experience any of the following symptoms, call your doctor immediately:

skin rash
difficulty breathing
swelling of the face
fever
vision problems or changes
difficulty hearing or ringing in the ears
faintness
easy bruising
unusual bleeding
sore throat
fast heartbeat
chest pain

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine? Return to top

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose Return to top

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What other information should I know? Return to top

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names Return to top

Quinamm®

Quiphile®

Last Revised - 03/01/2007
Last Reviewed - 08/01/2007

American Society of Health-System Pharmacists, Inc. Disclaimer