The combination of erythromycin and sulfisoxazole (a sulfa drug) is used to treat certain ear infections caused by bacteria. It usually is used in children.
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Erythromycin and sulfisoxazole comes as a liquid to take by mouth. It usually is taken every 6 hours (four times a day) for 10 days. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take erythromycin and sulfisoxazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Shake the liquid well before each use to mix the medication evenly.
Drink a full glass of water after each dose.
Continue to take erythromycin and sulfisoxazole even if you feel well. Do not stop taking erythromycin and sulfisoxazole without talking to your doctor.
Do not take this medication with, or just after, fruit juices, carbonated drinks, or tea. It can be taken with or between meals.
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
mild skin rash
severe skin rash
difficulty breathing or swallowing
yellowing of the skin or eyes
blood in urine
unusual bleeding or bruising
dark, tarry stools
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].
Keep this medication in the container it came in, tightly closed, and out of reach of children. Keep it in the refrigerator, and throw away any unused medication after 14 days. Do not freeze. Talk to your pharmacist about the proper disposal of your medication.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to erythromycin and sulfisoxazole.
Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the erythromycin and sulfisoxazole, call your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Last Revised - 08/01/2010
AHFS® Consumer Medication Information. © Copyright, 2014. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.