Pegfilgrastim is used to reduce the chance of infection in people who have certain types of cancer and are receiving chemotherapy medications that may decrease the number of neutrophils (a type of blood cell needed to fight infection). Pegfilgrastim is in a class of medications called colony stimulating factors. It works by helping the body make more neutrophils.
Pegfilgrastim comes as a solution (liquid) to inject subcutaneously (under the skin). It is usually given as a single dose for each chemotherapy cycle, no sooner than 24 hours after the last dose of chemotherapy of the cycle is given and more than 14 days before beginning the next chemotherapy cycle. Your doctor will tell you exactly when you should use pegfilgrastim.
Pegfilgrastim may be given to you by a nurse or other healthcare provider, or you may be told to inject the medication at home. If you will be injecting pegfilgrastim at home, follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use pegfilgrastim exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.
If you will be injecting pegfilgrastim yourself, a healthcare provider will show you how to inject the medication. Be sure that you understand these directions. Ask your healthcare provider if you have any questions about where on your body you should inject pegfilgrastim, how to give the injection, or how to dispose of used needles and syringes after you inject the medication.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Unless your doctor tells you otherwise, continue your normal diet.
If you will be injecting pegfilgrastim at home, talk to your doctor about what you should do if you forget to inject the medication on schedule.
redness, swelling, bruising, itching or a lump in the area where the medication was injected
bone, joint, or muscle pain
swelling of the arms, hands, feet, ankles, or lower legs
pain in the left upper part of the stomach or the tip of your left shoulder
shortness of breath
swelling around the mouth or eyes
Pegfilgrastim may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
Keep this medication in the carton it came in, tightly closed, and out of reach of children. Store pegfilgrastim in the refrigerator but do not freeze it. If you accidentally freeze the medication, you may allow it to thaw in the refrigerator. However, if you freeze the same syringe of medication a second time, you should throw away that syringe. Pegfilgrastim may be kept at room temperature for up to 48 hours but should be kept away from direct sunlight. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to pegfilgrastim.
Before having a bone imaging study, tell your doctor and the technician that you are using pegfilgrastim. Pegfilgrastim may affect the results of this type of study.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Last Reviewed - 09/01/2010
AHFS® Consumer Medication Information. © Copyright, 2014. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.