Ipilimumab injection may cause severe or life-threatening side effects. This includes inflammation of the intestine, which may cause tears in its walls; inflammation of the liver, which may cause severe liver damage; inflammation of the skin, which may cause a serious skin reaction; inflammation of the nerves, which may cause paralysis (loss of ability to move all or part of the body); inflammation of certain glands, which may affect how the glands work; or inflammation of the eyes. You may develop these symptoms during your treatment or during the first few weeks or months after you finish your treatment. If you experience any of the following symptoms, call your doctor immediately: diarrhea or frequent bowel movements; bloody or black, tarry, sticky stools; stomach pain or tenderness; yellowing of the skin or eyes; dark (tea-colored) urine; pain in the upper right part of the stomach; nausea or vomiting; easy bruising or bleeding; skin rash that may or may not be itchy; blistering or peeling skin; sores in the mouth; unusual weakness of the legs, arms, or face; numbness or tingling in the hands or feet; headaches that are unusual or that don't go away; sluggishness; feeling cold all the time; weight gain; decreased sex drive; irritability; forgetfulness; dizziness; changes in mood or behavior; fainting; blurred vision; double vision; other vision problems; or eye pain or redness. Call your doctor even if you feel that the symptoms you are experiencing are mild and do not try to treat your symptoms yourself. You may be able to prevent these side effects from becoming serious or life-threatening if you get treatment right away.
Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests before and during your treatment to see if it is safe for you to receive ipilimumab injection and to check your body's response to ipilimumab injection.
Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with ipilimumab injection and each time you receive a dose of the medication. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer's website to obtain the Medication Guide.
Talk to your doctor about the risks of receiving ipilimumab injection.
Ipilimumab injection is used to treat melanoma (a type of skin cancer) that cannot be treated with surgery or that has spread to other parts of the body. Ipilimumab injection is in a class of medications called monoclonal antibodies. It works by helping the body to slow or stop the growth of cancer cells.
Ipilimumab injection comes as a solution (liquid) to be injected intravenously (into a vein) over 90 minutes by a doctor or nurse in a hospital or medical facility. It is usually given once every 3 weeks for up to four doses.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Unless your doctor tells you otherwise, continue your normal diet.
Some side effects can be serious. If you experience any of the symptoms listed in the IMPORTANT WARNING section, call your doctor immediately.
Ipilimumab injection may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Ask your pharmacist any questions you have about ipilimumab injection.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Last Revised - 05/15/2014
AHFS® Consumer Medication Information. © Copyright, 2014. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.