Asparaginase Erwinia chrysanthemi is used with other chemotherapy medications to treat acute lymphocytic leukemia (ALL; a type of cancer of the white blood cells). It is used in patients who have had some types of allergic reactions to medications similar to asparaginase Erwinia chrysanthemi such as (asparaginase [Elspar] or pegaspargase [Oncaspar]). Asparaginase Erwinia chrysanthemi is an enzyme that interferes with natural substances necessary for cancer cell growth. It works by killing or stopping the growth of cancer cells.
Asparaginase Erwinia chrysanthemi comes as a powder to be added to fluid and injected into a muscle by a doctor or nurse in a medical facility. It is usually given three times a week.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Unless your doctor tells you otherwise, continue your normal diet.
If you miss an appointment to receive a dose of asparaginase Erwinia chrysanthemi, call your doctor right away.
difficulty breathing or swallowing
ongoing pain that begins in the stomach area, but may spread to the back
arm or leg swelling
shortness of breath
yellowing of the skin or eyes
pain in the upper right part of the stomach
dark colored urine
loss of appetite
lack of energy
Asparaginase Erwinia chrysanthemi may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to asparaginase Erwinia chrysanthemi.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Last Revised - 12/15/2012
AHFS® Consumer Medication Information. © Copyright, 2015. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.