Unilateral hydronephrosis is swelling of one kidney due to a backup of urine.
See also: Bilateral hydronephrosis
Hydronephrosis (kidney swelling) is a condition that occurs with a disease. It is not a disease itself. Conditions that are often associated with unilateral hydronephrosis include:
Unilateral hydronephrosis occurs in approximately 1 in 100 people.
Note: Sometimes unilateral hydronephrosis does not have symptoms.
Unilateral hydronephrosis is found on an imaging test such as:
Treatment and prognosis for unilateral hydronephrosis depend on what is causing the kidney swelling. Treatment may include:
Patients who have only one kidney, who have immune-compromising disorders such as diabetes or HIV, or who have received a transplant should be treated promptly.
Preventative antibiotics may be prescribed to decrease the risk of urinary tract infections in patients who have long-term hydronephrosis.
Prolonged hydronephrosis results in the eventual loss of kidney function.
If hydronephrosis is left untreated, the affected kidney may be permanently damaged. Kidney insufficiency or kidney failure is rare with unilateral hydronephrosis because the other kidney usually functions normally. However, if the patient has only one functioning kidney, kidney failure will occur.
Call your health care provider if you have prolonged or severe flank pain, or if you suspect hydronephrosis.
Prevention of the disorders associated with unilateral hydronephrosis will prevent this condition.
Hydronephrosis; Chronic hydronephrosis; Acute hydronephrosis; Urinary obstruction
Zeidel ML.Obstructive uropathy. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 125.
SinghI, Strandhoy JW, Assimos DG. Pathophysiology of urinary tract obstruction. In: Wein AJ, ed.Campbell-Walsh Urology. 10th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 40.
Updated by: Linda J. Vorvick, MD, Medical Director and Director of Didactic Curriculum, MEDEX Northwest Division of Physician Assistant Studies, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington. Louis S. Liou, MD, PhD, Chief of Urology, Cambridge Health Alliance, Visiting Assistant Professor of Surgery, Harvard Medical School. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc.
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