Propoxyphene is medicine used to relieve pain. Propoxyphene overdose occurs when someone takes too much of this medicine.
The U.S. Food and Drug Administration (FDA) took this drug off the market in December 2010 because of the potential to cause deadly heart disturbances.
This is for information only and not for use in the treatment or management of an actual poison exposure. If you have an exposure, you should call your local emergency number (such as 911) or 1-800-222-1222 to find a local poison control center.
Brand names include:
Note: This list may not be all-inclusive.
Eyes, ears, nose, and throat:
Heart and blood vessels:
Stomach and intestines:
Seek immediate medical help. DO NOT make a person throw up unless told to do so by Poison Control or a health care professional.
Determine the following information:
In the United States, call 1-800-222-1222 to speak with a local poison control center. This hotline number will let you talk to experts in poisoning. They will give you further instructions.
This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. You can call 24 hours a day, 7 days a week.
The health care provider will measure and monitor the patient's vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms, including heart rhythm disturbances and seizures, will be treated as appropriate
The patient may receive:
If the proper narcotic antagonist can be given, recovery from an acute overdose occurs within 24 - 48 hours.
Propoxyphene hydrochloride; Dextropropoxyphene
Goldfrank LR, ed. Goldfrank's Toxicologic Emergencies. 9th ed. New York, NY: McGraw Hill; 2011.
Updated by: Eric Perez, MD, St. Luke's / Roosevelt Hospital Center, NY, NY, and Pegasus Emergency Group (Meadowlands and Hunterdon Medical Centers), NJ. Review provided by VeriMed Healthcare Network. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, Bethanne Black, Stephanie Slon, and Nissi Wang.
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