Apolipoprotein B100 (apo B100) is a protein that plays a role in moving cholesterol around your body. It is a form of low density lipoprotein (LDL).
This article discusses the test used to measure the level of apoB100 in the blood.
A blood sample is needed. For information on how this is done, see: Venipuncture
Your health care provider may tell you not to eat or drink anything for 4 - 6 hours before the test.
When the needle is inserted to draw blood, you may feel moderate pain, or only a prick or stinging sensation. Afterward, there may be some throbbing.
Most often, this test is done to help determine the cause or specific type of hyperlipidemia.
The normal range is 50 - 150 mg/dL.
Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
The examples above show the common measurements for results for these tests. Some laboratories use different measurements or may test different specimens.
An abnormal result may mean you have high lipid levels (hyperlipidemia).
See also: Familial combined hyperlipidemia
Apolipoprotein measurements may provide more detail about your risk for heart disease, but the added value of this test beyond a lipid panel is unknown.
ApoB100; Apoprotein B100
Genest J, Libby P. Lipoprotein disorders and cardiovascular disease. In: Bonow RO, Mann DL, Zipes DP, Libby P, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 9th ed. Philadelphia, PA:Saunders Elsevier; 2011:chap 47.
Semenkovich, CF. Disorders of lipid metabolism. In: GoldmanL, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 213.
Updated by: David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc. David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc.
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